Rethinking anemia: does blood hemoglobin tell the whole story?
NCT ID NCT07761104
First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time
Summary
This study asks whether the standard blood hemoglobin concentration accurately reflects the body's true oxygen-carrying capacity in adults with non-life-threatening anemia arriving at the emergency department. Participants will undergo additional tests, including a carbon monoxide rebreathing technique to measure total hemoglobin mass, echocardiography, and tissue oxygen monitoring. The goal is to see if these advanced measurements reveal a more complete picture of anemia's severity than routine blood tests alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Measurement of total hemoglobin mass using carbon monoxide rebreathing, plus echocardiography, near-infrared spectroscopy, and blood rheology tests
- What this could lead to
- If successful, this could lead to better ways to assess anemia severity in emergency settings, improving treatment decisions.
- What could go wrong
- This is a small, early-stage observational study. The measurements may not translate into routine clinical practice, and the results may not apply to all anemic patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Emergency department, Edouard Herriot Hospital, Hospices Civils de Lyon
Lyon, 69003, France
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