Centre Hospitalier Universitaire De Nice

This study looked at whether taking oral azacitidine (Onureg) as maintenance therapy can help older adults with acute myeloid leukemia (AML) stay in remission longer after treatment with CPX-351 chemotherapy. The study included 100 patients aged 65 and older who had achieved remi…

This trial investigates whether bosentan, a drug that blocks endothelin and relaxes blood vessels, can help people who suddenly lose vision from giant cell arteritis (Horton's disease). Standard steroid treatment often fails to restore sight once blindness occurs. The study enrol…

This phase 3 trial tested whether methotrexate, a drug used for other types of arthritis, can reduce pain and improve quality of life in people with erosive hand osteoarthritis. 64 participants received either methotrexate or a placebo once a week for 12 months. The study measure…

This study compared two types of ultraviolet light treatments—an excimer lamp and an excimer laser—for repigmenting white patches caused by vitiligo. Adults with at least two matching patches of vitiligo received both treatments on different patches twice a week for 12 weeks. The…

This pilot study tested whether metformin, a common diabetes drug, could help treat advanced melanoma that had spread and stopped responding to other treatments. Twenty adults with stage IIIC or IV melanoma took metformin to see if it could shrink their tumors. The goal was to fi…

This study tested whether giving a clot-busting drug directly into the brain's fluid spaces could save lives after a severe brain bleed caused by a burst aneurysm. Nineteen patients with heavy bleeding inside the brain's chambers received the treatment. The main goal was to see i…

This Phase 3 trial tested whether low doses of interleukin-2 (IL2) can help people with severe alopecia areata, a condition causing patchy or total hair loss. 44 adults with at least 50% scalp hair loss who had not responded to other treatments received either IL2 injections or a…

This study tested whether the drug apremilast, taken as a pill twice daily, combined with narrowband UVB light therapy can help restore skin color in people with widespread vitiligo. 80 adults with stable or slowly progressing vitiligo covering at least 10% of their body took par…

This study tested a new material called Mucoderm, made from donated animal tissue, to treat receding gums. It compared it to the standard treatment, which uses a small piece of tissue from the patient's own palate. The goal was to see if Mucoderm could cover exposed tooth roots j…

This phase 2 trial tested avdoralimab, an antibody that blocks a specific immune signal, added to standard steroid cream for bullous pemphigoid—a severe blistering skin condition mostly affecting older adults. Fifteen participants received the combination to see if it leads to co…

This study tested whether a probiotic called Lactobacillus rhamnosus Lcr35® can reduce the number of painful canker sores in people who get them often. Twenty adults with frequent outbreaks took either the probiotic or a placebo daily for 3 months, then were monitored for another…

This study tested whether giving people with spondyloarthritis a connected activity tracker and sending them text reminders to exercise could help them stay active and reduce disease flares. 108 adults with stable spondyloarthritis were split into two groups: one got the tracker …

This study tested whether adding the cholesterol drug atorvastatin to standard UVB light therapy works better than UVB alone for active vitiligo. 28 adults with active, non-segmental vitiligo took part. The main goal was to see if the combination reduced the amount of skin color …

This study tested a gel called Picato (ingenol mebutate) on 20 people with a very early form of melanoma on the face, called lentigo maligna. Participants applied the gel once a day for three days. The goal was to see if the gel could make the cancer disappear completely, offerin…

This study tested whether starting treatment early with UVB light therapy and low-dose steroids can stop vitiligo from spreading and improve skin color return. 51 people with different stages of vitiligo were treated for 6 months. Researchers took skin samples to see how immune c…

This completed pilot study tested whether a computer algorithm could diagnose facioscapulohumeral muscular dystrophy (FSHMD) by analyzing video recordings of people's faces. Researchers recorded 17 participants, including patients with FSHMD, other muscle diseases, and healthy co…

This study compared two imaging methods for diagnosing female infertility: MRI with a contrast dye and traditional X-ray. The goal was to see if MRI, which uses no radiation, could provide a complete and accurate assessment. Forty women participated, and researchers measured how …

This study tested whether a blood test can detect ALK gene rearrangements in lung cancer patients, which currently requires an invasive tumor biopsy. Researchers analyzed circulating tumor cells from blood samples of 206 patients with advanced lung cancer. The goal was to see if …

This study looked at whether a blood test for circulating tumor cells (CTCs) can help detect lung cancer earlier in people at very high risk: smokers and ex-smokers with COPD. Researchers combined this blood test with low-dose CT scans over three yearly screenings in 683 particip…

This study tested whether a special ultrasound with contrast dye can be as good as CT scans for checking aortic endoprostheses after abdominal aortic aneurysm repair. Forty patients received both an ultrasound and a CT scan after surgery. The goal was to see if ultrasound could d…

This study looked at whether a substance called glicentin in the blood can help diagnose intestinal ischemia, a condition where blood flow to the gut is blocked. Researchers measured glicentin levels in 54 people with suspected ischemia and compared them to a control group. The g…

This study tested a new bioimpedance device that measures muscle mass while seated, without sticky electrodes, against the standard osteodensitometry scan. Researchers enrolled 72 adults aged 60 and older to see if the simpler method gives accurate results for diagnosing sarcopen…

This study looked at whether a blood test measuring the sFlt-1/PlGF ratio can help doctors decide if women with suspected pre-eclampsia need to be hospitalized. Pre-eclampsia is a serious pregnancy condition that can harm both mother and baby, but diagnosing it is tricky. The stu…

This study followed 111 pregnant women to see how iodine supplements affect thyroid function throughout pregnancy. Researchers measured thyroid hormones and checked for complications like miscarriage or low birth weight. The goal was to find better ways to prevent iodine deficien…

This study tests whether tranexamic acid, a drug used to control bleeding, can prevent dark spots that often appear after skin inflammation. Ten healthy men at risk for hyperpigmentation will take the drug and have small blisters created on their skin to trigger the spots. Resear…

This study looks at whether adding a physical activity education program to adapted exercise helps people with mild memory or thinking problems more than exercise alone. Thirty-four participants will be followed for six months to measure changes in activity level, thinking skills…

This study explores whether regular, supervised meetings between socially isolated seniors (65+) and disadvantaged children (kindergarten to elementary school) can reduce loneliness in seniors and improve children's school behavior. Over 7 months, pairs meet weekly for 1.5 hours,…

This study tested a cream made from green tea extract (Veregen) on 6 people with lamellar ichthyosis, a rare genetic condition that causes severe dry, scaly skin. Participants applied the cream to one side of their body and a standard moisturizer to the other for 4 weeks. The goa…

This study looked at whether a weekly hour of adapted physical activity for 12 weeks could improve self-esteem and motivation in 17 older adults with mild to major cognitive disorders like Alzheimer's. Researchers measured changes in self-esteem, motivation, and apathy. The goal …

This study tested whether a TENS device, which sends mild electrical pulses through the skin, can reduce leg pain in people with Charcot-Marie-Tooth disease. Ten adults with chronic pain participated. The goal was to see if pain scores dropped by at least 30%.

This study tested whether a special lung-opening maneuver during anesthesia can reduce breathing problems and oxygen needs after weight-loss surgery. Researchers studied 230 obese patients undergoing bariatric surgery. Half received the extra lung-opening procedure, while the oth…

This study tested whether a gas called MEOPA (laughing gas) can help elderly people manage pain during physiotherapy for stiff hips or knees. Six patients aged 65 or older received three sessions of physiotherapy with MEOPA or standard care. The goal was to see if the gas improve…

This small study tested whether using a rocking chair for an hour each day could help reduce agitation in elderly people with dementia. Twelve nursing home residents took part in daily rocking sessions for six weeks. Researchers measured changes in agitation, use of calming medic…

This study compared two similar painkillers—esketamine and ketamine—given as low-dose injections to 74 adults with severe acute pain in the emergency department. The main goal was to see which drug caused fewer disturbing mental side effects like hallucinations or dizziness. Both…

This study tested a minimally invasive procedure called CT-guided trans-facet screw fixation for 24 patients whose spine became unstable after a prior back surgery (laminectomy). Instead of open surgery under general anesthesia, the procedure uses a CT scan to guide small screws …

This study tested whether combining ketamine with propofol reduces agitation during recovery from sedation, compared to ketamine alone. 150 adults needing sedation for a broken bone or dislocation were randomly assigned to one of the two drug combinations. The main goal was to se…

This study tested whether an injection of etanercept, a targeted anti-inflammatory drug, works better than a standard steroid injection for sudden joint swelling in people with rheumatoid arthritis. 34 adults with active arthritis in a knee, wrist, ankle, or elbow took part. The …

This study tested whether using a low-frequency laser on an acupuncture point (P6) can help prevent nausea and vomiting caused by chemotherapy in children aged 2 to 20. The 30 participants received the laser treatment alongside standard anti-nausea drugs. The goal was to see if a…

This study tested whether adding a special antioxidant pill (GLISODIN) to standard UVB light therapy helps treat vitiligo better than light therapy alone. Fifty adults with non-segmental vitiligo covering more than 5% of their body took part. The main goal was to see if the combi…

This study tested whether stimulating two brain areas at once—the anterior cingulate cortex (involved in pain emotions) and the sensory thalamus (involved in pain sensation)—is safe and feasible for treating chronic nerve pain that hasn't responded to other treatments. Eight adul…

This study tested whether eccentric muscle training (lengthening exercises) improves walking performance in people with knee osteoarthritis compared to standard concentric training (shortening exercises). Forty adults aged 40-85 with knee osteoarthritis participated in 6 weeks of…

This study tested whether a connected knee brace with a phone app could improve muscle strengthening rehab for people with knee osteoarthritis. 65 adults aged 50-80 used either standard rehab or the smart brace with remote physiotherapist supervision for 8 weeks. The goal was to …

This study tested a new cream for melasma, a skin condition causing dark patches. The new cream uses thiamidol instead of hydroquinone, which often causes side effects. 40 adults with melasma tried either the new cream or the standard treatment to see if it works as well but is g…

This study tested a computer-controlled method of giving propofol sedation to 45 adults in the emergency department. The goal was to find the right brain concentration needed for deep sedation during painful procedures like fixing a broken bone or putting a dislocated joint back …

This study tested a newer, gentler type of keyhole surgery for removing the appendix. It uses lower gas pressure and smaller instruments than standard laparoscopy. Fifty adults with uncomplicated appendicitis took part, and the researchers measured their pain, recovery time, and …

This study looked at whether hypnosis can reduce itching in people with chronic idiopathic pruritus (long-term itching with no known cause). Twelve adults with moderate to severe itching received hypnosis sessions. Researchers measured changes in itch intensity, sleep quality, an…

This study tested whether a specific nerve block (called Quadratus Lumborum Block type 3) can reduce pain and the need for strong painkillers after total hip replacement surgery. Sixty adults having hip replacement were randomly given either the nerve block with a numbing medicin…

This study tested whether using virtual reality (VR) during medical procedures can reduce pain and anxiety in hospitalized patients over 60. 87 elderly participants used VR headsets or tablets showing relaxing scenes while receiving routine care. The goal was to see if personaliz…

This study looked at placing a small metal tube (stent) into the portal vein of 63 cancer patients whose vein was blocked by a tumor. The goal was to relieve serious symptoms like fluid buildup in the belly or bleeding in the gut. The procedure was done through a needle in the li…

This study looks at how different amounts of endurance exercise—from none to high levels—affect the bacteria living in the mouth of young adults aged 18 to 30. Researchers will collect saliva and gum samples to compare the oral microbiome and signs of inflammation. The goal is to…

This study follows 1500 adults with interstitial lung disease to understand how the condition changes over time. Researchers will track symptoms, lung function, and treatments used. The goal is to build a detailed picture of the disease's course and improve future care.

This study looked at how the COVID-19 lockdown affected people with spondyloarthritis, a type of arthritis. Researchers surveyed 1,000 patients to see if they stopped their usual treatments during confinement and what psychological factors might have played a role. The goal was t…

This pilot study looked at whether special scans (18FDG PET-CT) and blood tests could help predict how well CAR T-cell therapy works for people with hard-to-treat non-Hodgkin's lymphoma. Twenty patients were followed for up to a year after treatment. The goal was to see if these …

This completed study from France examined joint fluid from 20 people with arthritis to see if acid-sensing ion channels (ASICs) play a role in pain. Researchers wanted to find natural compounds that activate these channels during inflammation. The goal is to validate ASICs as tar…

This study looked at whether a blood test called ISET can find circulating tumor cells in people with early-stage non-small cell lung cancer. Researchers checked blood samples from 256 patients before surgery to see if these cells were linked to cancer stage, type, and survival. …

This study looked at 6 children with past PTSD to see if changes in attention and memory could predict a relapse. Researchers used computer tasks and standard tests to measure brain function. The goal is to find early warning signs so families can get help sooner.

This study looked at 30 adults aged 40-70 with treatment-resistant depression to see if changes in thinking skills (like memory and attention) could predict when depression improves. Researchers measured mood, daily function, and cognitive abilities before and after starting a ne…

This study looked at 100 patients who had sleeve gastrectomy for severe obesity. Researchers checked how many developed Barrett's esophagus, a condition that can lead to esophageal cancer, five or more years after surgery. They also examined whether routine endoscopy (a camera te…

This completed pilot study aimed to estimate how common osteoporosis is in France, starting with the Alpes-Maritimes region. Researchers enrolled 800 participants who each received a bone densitometry scan. The study was observational and did not test any treatment.

This study looked at 20 people with hard-to-treat chronic cluster headache who were already receiving occipital nerve stimulation. Researchers used brain scans to see how the stimulation changes brain activity. The goal was to understand how the treatment works, not to test if it…

This study looked at 180 people with liver cancer (hepatocellular carcinoma) who also had cirrhosis caused by either fatty liver disease or alcohol use. Researchers compared immune cells and gut bacteria in the liver to understand why cancer develops. The goal was to gather knowl…

This study aimed to understand why people with cochlear implants vary in how well they understand speech. Researchers measured electrical interactions between the implant's electrodes in 17 adults with hearing loss. They compared these measurements to each person's ability to rec…

This study looks at whether gastric bypass surgery can protect the kidneys of people who are severely obese and have chronic kidney disease. Researchers measured kidney function before and one year after surgery in 14 patients. The goal is to see if the surgery improves the balan…

This study looked at colon tissue samples from 200 people with irritable bowel syndrome (IBS) to understand why their gut barrier may be leaky. Researchers tested whether substances released by mast cells (a type of immune cell) can damage the gut lining and nerves. The goal is t…

This study tested whether a new 3D ultrasound technique can predict how well patients with pulmonary hypertension will do. Researchers followed 150 patients for six months, collecting heart images and tracking deaths and hospitalizations. The goal was to see if this non-invasive …

This study looked at whether French doctors follow EULAR recommendations to check heart disease risk every year in patients with rheumatoid arthritis. Over 7000 patients were included. The goal was to see how often tests like blood sugar, cholesterol, and heart scans were prescri…

This study observed 30 elderly patients (over 65) who had a specific type of neck fracture (odontoid fracture) from a minor fall or low-energy injury. Researchers measured bone density, vitamin D levels, and other bone health markers to understand why these fractures happen. They…

This study looks at whether people with chronic inflammatory rheumatism (like spondyloarthritis) or lupus who still have pain despite treatment have low vitamin C levels. Researchers will measure vitamin C in the blood and ask about pain, fatigue, and quality of life. The goal is…

This completed study surveyed 566 adolescents aged 14 to 16 to understand how jaw pain (temporomandibular disorders) relates to other painful conditions like headaches, neck pain, and back pain. Researchers used anonymous questionnaires to identify common co-occurring health issu…

This study looked at 468 divers treated for suspected diving accidents at Nice University Hospital between 2014 and 2025. Researchers analyzed details like age, dive depth, and duration to see if certain health factors are linked to decompression sickness even when divers follow …

This study tested a 4-session education program for people with early schizophrenia. The goal was to see if it helps patients feel more connected to their therapist, which is important for ongoing care. 21 hospitalized patients took part, and researchers measured changes in the p…

This completed study looked at how immune cells recover in 61 adults who received a stem cell transplant for blood cancers. Researchers measured the function of T and NK cells by testing their cytokine profiles after stimulation. The goal was to see if these measurements could he…

This study tested a new care plan for 100 low-risk mothers and their newborns, allowing them to go home within 24 hours after a normal vaginal delivery. Participants received daily visits from a midwife for the first three days and used a special mobile app to stay in touch with …

This study tested new ways to measure how hard older adults exercise during physical activity sessions. The goal was to make exercise programs more personalized and reduce injury risk. 87 adults over 65 took part, and researchers compared different methods to estimate exercise in…

This study looked at how hormones and birth control pills affect knee ligament looseness in healthy women. Researchers measured knee laxity in 45 women at two points in their menstrual cycle, comparing those on hormonal contraceptives to those not. The goal was to better understa…

This completed study investigated whether air pollution affects flare-ups in people with rheumatoid arthritis, ankylosing spondylitis, or psoriatic arthritis. Researchers followed 86 patients for 6 months, asking them to complete weekly questionnaires about their symptoms. They a…

This study looked at 56 patients in a French hospital who had infections from a rare type of Klebsiella pneumoniae bacteria that can be treated with the common antibiotic amoxicillin. Researchers used genetic sequencing to understand why these bacteria are sensitive to amoxicilli…

This study looked back at 420 patients who had jaw surgery after using either clear aligners or traditional metal braces. The goal was to see if the type of orthodontic preparation affected how smoothly the surgery went. Researchers checked things like how stable the jaw was duri…

This study examined whether arthritis in the hands is linked to more severe arthritis in the knees and hips. Researchers used hand X-rays to assess joint damage in 479 adults aged 40 to 75 with confirmed knee or hip arthritis. The goal was to better understand how arthritis progr…

This study looked at 22 people with advanced (Stage IV) melanoma to see if DNA floating in their blood could show genetic changes in their cancer before and after chemotherapy. Researchers compared the DNA found in blood samples with the original tumor's genetics. The goal was to…

This completed study looked at how the drug Advagraf (a form of tacrolimus) works in 45 adults who received a kidney transplant. The goal was to find better ways to dose the drug by measuring its levels in the blood right after transplant and three months later. Researchers compa…

This early-phase study in 40 healthy adults explores how the immune system reacts to the non-toxic part of cholera toxin (CTB) when given through the nose, mouth, or under the tongue. The goal is to understand mucosal immune responses, which could help in developing future vaccin…

This study looked at whether giving iodine supplements to pregnant women helps their children's brain development. Researchers tested 85 children at age 2 using a standard developmental assessment. The goal was to see if iodine, which is often low in French diets, makes a differe…

This study looked at skin samples from 170 people with psoriasis, atopic dermatitis (eczema), or healthy skin to understand how a protein called Lyn is involved in inflammation. Researchers measured Lyn activity and related enzymes in both affected and unaffected skin. The goal w…

This completed study examined immune semaphorin proteins in the liver and fat tissue of 148 obese patients with non-alcoholic fatty liver disease (NAFLD). Researchers aimed to understand how these proteins relate to inflammation and liver damage. The study did not test any treatm…

This study looked at sleep disturbances in people with Alzheimer's disease. Researchers tracked sleep diaries, activity levels, and behavior in 70 participants to understand how disrupted sleep relates to daily cycles and daytime alertness. The goal was to learn more about the li…

This study looked at whether exposure to certain chemicals (endocrine disruptors) during pregnancy might increase the chance of a baby boy being born with undescended testicles. Researchers compared 95 affected boys with 188 healthy boys, testing cord blood and breast milk for th…

This study followed 29 infants who had bronchiolitis in their first year to see if their lung function changes over time and whether that leads to asthma. Researchers measured breathing using special tests and also did allergy skin tests. However, many families dropped out, so th…

This completed study looked at how teenagers with autism or schizophrenia understand emotions, metaphors, and social situations compared to healthy teens. Researchers tested 60 participants using facial emotion recognition and other tasks. The goal was to find out if social diffi…

This study looked at 30 people with cystinosis, a rare disease that causes crystals to build up in the body. Researchers wanted to understand why some patients have lighter skin patches and how this relates to the disease. They studied genetic and skin samples to find the molecul…

This study looked at whether a special kidney scan (scintigraphy) can find early kidney damage in children and young adults with sickle cell disease better than standard tests. 18 patients were checked during their annual visit. The goal is to catch kidney problems sooner so trea…

This study looked at 659 patients who had surgery to fix an abdominal aortic aneurysm. Researchers compared two types of scans—CT and ultrasound—to see which one is better at finding problems like leaks or blockages after the repair. The goal was to find out if ultrasound could b…

This pilot study looked at 38 liver transplant patients to see if liver failure lowers blood levels of pyrophosphate, a natural substance that prevents calcium buildup in tissues. Researchers measured pyrophosphate before and after transplant and checked liver tissue for a relate…

This study explored whether the Epstein-Barr virus (EBV) contributes to inflammation in oral lichen planus, a chronic mouth condition that can be painful. Researchers measured levels of EBV genetic material in 13 adults with the atrophic or erosive form of the disease. The goal w…

This study tested how accurately a robot system called Neurolocate helps place electrodes in the brain during deep brain stimulation surgery. It involved 18 adults with Parkinson's disease, dystonia, or tremor. The goal was to see if the robot could improve precision, reduce surg…

This study tested whether a type of eye scan called OCT-angiography can predict how well vision will recover after surgery to remove a pituitary tumor. Researchers compared the scan results with standard vision tests in 21 patients. The goal was to see if the scan could serve as …

This study tested whether a blood sample can predict how severe COVID-19 will become in kidney transplant patients with mild to moderate symptoms. Researchers measured a protein called IL-6 after stimulating the blood sample. They followed 52 patients to see if IL-6 levels were l…

This study looked at the mental health of hospital staff and medical students after the 2016 Nice terrorist attack. Researchers surveyed 804 people to understand how the event affected them and to find better ways to support caregivers in future crises. The goal was to learn, not…

This study looked at whether blue light from computer and TV screens can make melasma (a common skin condition causing dark patches on the face) worse. Twelve women with melasma had one side of their face exposed to blue light for 30 minutes a day over 5 days, while the other sid…

This study looked at gene activity in cells from the nose and lungs of 44 healthy and allergic adults. The goal was to understand how allergies change these cells and why the nose and lungs react differently. Researchers hope this knowledge will lead to better treatments for alle…

This study looked at whether measuring venous lactate (a waste product in the blood) during CPR can help predict if a person's heart will start beating again after a cardiac arrest outside the hospital. Researchers tested lactate levels in 77 adults when emergency teams arrived. …

This completed study looked at how apathy (lack of motivation) influences different forms of fatigue in 57 older adults with mild cognitive disorders. Participants wore an activity tracker for a week and completed tests like a 6-minute walk and questionnaires. The goal was to com…

This study looked at whether a personalized physical activity program could help older adults who are frail or at risk of becoming frail. Nearly 1,000 participants aged 65 and older had their strength, thinking skills, and well-being assessed. They then received a custom exercise…

This study aims to create a detailed map of the cells lining the airways in healthy people. By analyzing gene activity in individual cells from different parts of the respiratory tract, researchers hope to better understand how these cells interact and how diseases like asthma de…

This study looked at whether adding diluted epinephrine to the numbing drug ropivacaine during a TAP block (a pain block for abdominal surgery) lowers the peak amount of ropivacaine in the blood. Forty adults having laparoscopic colectomy received either ropivacaine alone or with…

This study looked at proteins in the eye fluid of 100 people with wet age-related macular degeneration (AMD). The goal was to measure certain growth factors that might explain why about 37% of patients do not respond well to standard anti-VEGF injections. Researchers collected a …

This study looked at two different ways of giving the antibiotic cloxacillin to treat bone and joint infections caused by Staphylococcus aureus bacteria. Twelve patients received the drug both as a steady drip (continuous infusion) and as short doses (intermittent infusion) to se…

This study tested whether shining different colors of LED light (630nm, 830nm, and 590nm) on skin could speed up healing after a laser made small wounds. Ten healthy volunteers had tiny areas on their forearms treated with a fractional CO2 laser, then exposed to LED or no light. …

This study looked at how mental and muscle fatigue affect older adults' ability to walk and do a counting task at the same time. 66 participants, both young (20-40) and older (65-90), completed walking and counting tests before and after fatigue tasks. The goal was to understand …

This completed lab study took blood samples from 20 adults with relapsed membranous nephropathy, a kidney condition. Researchers tested different immune-modulating drugs on the blood cells to see how they affect the balance of Th17 and Treg immune cells. The goal is to find which…

This study tested a blood test called ELISpot to see if it can detect the body's immune response to the COVID-19 virus. The test aims to find infections that standard swab tests might miss and help predict whether a person will develop mild or severe illness. Researchers enrolled…

This study looked at a process called autophagy, which is how cells clean out damaged parts, in 82 women over 65 with osteoporosis. Some also had Alzheimer's disease. Researchers measured autophagy levels in bone cells from hip samples to see if poor cell cleanup links bone loss …

This completed study looked at how people with Alzheimer's disease search for objects in realistic scenes and real-life settings. Researchers tracked eye movements in 48 participants to understand which attention and memory processes are impaired. The goal was to link visual expl…

This pilot study examined whether inflammation, measured by cytokines in the blood, plays a role in type 1 facioscapulohumeral muscular dystrophy (FSHD1). Researchers compared 20 FSHD1 patients with healthy controls to see if certain inflammatory markers are higher in the disease…

This study looks at a new blood test that measures specific antibodies in people with membranous nephropathy, an autoimmune kidney disease. The test aims to predict which patients are more likely to develop kidney failure. Researchers will follow 52 adults over time to see if the…

This completed study looked at how radiation therapy for head and neck cancers affects viruses in the mouth, specifically the Epstein-Barr virus (EBV), and how this might relate to gum disease. Researchers collected samples from 25 patients to measure virus levels. The goal was t…

This study compares skin samples from 20 people with vitiligo and 20 healthy volunteers to understand why certain body areas (like the face) repigment well while others (like hands and feet) do not. Researchers will analyze gene activity in skin from five different body sites. Th…

This pilot study looks at how the brain controls fine hand movements and speech, using MRI scans in 20 healthy right-handed adults aged 18-35. Participants first practice motor and facial tasks for two weeks, then have an MRI while performing similar tasks. The goal is to find sh…

This study tested whether a mobile app (myFSHD) can help doctors monitor patients with facioscapulohumeral muscular dystrophy (FSHD) remotely. 70 adults with FSHD used the app at home for 12 months, completing questionnaires and video-recorded exercises. The goal was to see if pa…

This study examined 30 adults with dental implants to see if the Epstein-Barr virus (EBV) is linked to peri-implantitis, a disease that can cause implant loss. Researchers measured virus levels in gum samples and compared them to the severity of gum pockets. The goal was to bette…

This pilot study looked at 20 adults with acute myeloid leukemia (AML) who were not healthy enough for strong chemotherapy. They received a standard combination of azacitidine and venetoclax. Researchers measured venetoclax levels in the blood at several time points to see if tho…

This study looked at 93 people who had a stem cell transplant for blood cancer. Researchers wanted to see if chronic mouth problems (oral cGVHD) could be a simple sign that the new immune system is also attacking the cancer. They followed patients with regular mouth exams before …

This study used a computer model (digital twin) of one patient's jaw to compare three different dental implant configurations for people with severe bone loss. The goal was to see which setup distributes chewing forces most safely when teeth are loaded immediately after surgery. …

This completed study looked at 150 adults with thoraco-lumbar spine injuries to see if adding an emergency MRI to a standard CT scan changes how doctors treat them. The researchers compared treatment plans before and after the MRI, including options like rest, minimally invasive …