Could a common arthritis drug ease hand pain?
NCT ID NCT01068405
First seen Jun 22, 2026 · Last updated Jun 22, 2026
Summary
This study tested whether methotrexate, a drug used for other types of arthritis, can reduce pain and improve quality of life in people with erosive hand osteoarthritis. 64 participants received either methotrexate or a placebo once a week for 12 months. The goal was to see if methotrexate could help where no effective treatment currently exists.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Nice University Hospital, Rheumatology Department
Nice, 06000, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Methotrexate
What this could lead to
If it works, this could point toward a treatment for painful hand arthritis where none currently exists.
What could go wrong
This is a small, completed trial with only 64 participants. Methotrexate is an older drug with known side effects, and the results may not apply to all patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.