New knee system aims to improve mobility after failed replacement

NCT ID NCT04821154

Recruiting now Disease control Sponsor: Zimmer Biomet Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study is testing a new knee replacement system called Persona Revision for people who need a second knee replacement surgery. The goal is to see if it improves knee function, reduces pain, and is safe. About 380 adults will be followed for two years after surgery.

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Conditions

The condition(s) this trial relates to.

collagenopathy Infections infectious disease osteoarthritis osteoarthritis, knee polyarticular arthritis rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARTHROPLASTY COMPLICATIONS INFECTION KNEE DISEASE KNEE OSTEOARTHRITIS

Contacts and locations

Locations

Advanced Orthopaedic Specialists
RECRUITING

Fayetteville, Arkansas, 72703, United States
Arthroplasty Foundation Inc.
COMPLETED

Louisville, Kentucky, 40220, United States
Ascension Providence Rochester Hospital
RECRUITING

Rochester, Michigan, 48307, United States
Bowen Hefley Orthopedics
RECRUITING

Little Rock, Arkansas, 72205, United States
Community Foundation Medical Group
WITHDRAWN

Fresno, California, 93720, United States
Cornerstone Orthopaedics & Sports Medicine
COMPLETED

Superior, Colorado, 80027, United States
Jeff Yergler, LLC
RECRUITING

Granger, Indiana, 46530, United States
Michigan Orthopaedic Surgeons, PLLC
RECRUITING

Southfield, Michigan, 48076, United States
Orthopaedic Associates, Inc.
COMPLETED

Evansville, Indiana, 47710, United States
Orthopaedic Research Institute of New Jersey
RECRUITING

Chester, New Jersey, 07390, United States
Orthopedic Surgeons of Wisconsin, SC
WITHDRAWN

Wauwatosa, Wisconsin, 53222, United States
Penn Medicine/ Lancaster General Health
COMPLETED

Lancaster, Pennsylvania, 17602, United States
ROC Orthopedics
COMPLETED

Oregon City, Oregon, 97045, United States
TRIA Orthopaedic Center Research Institute
COMPLETED

Bloomington, Minnesota, 55431, United States
The Cleveland Clinic Foundation
RECRUITING

Cleveland, Ohio, 44195, United States
Thomas Aleto MD, PC
WITHDRAWN

Columbia, Missouri, 65201, United States

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