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New knee implant tested for better mobility and less pain

NCT ID NCT07286513

ENROLLING_BY_INVITATION Disease control Sponsor: Zimmer Biomet Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a new knee implant called the Persona SoluTion PPS femur in 200 adults who need total knee replacement. The goal is to see if it safely improves knee function and reduces pain over two years. Participants will have their knee health measured before surgery and at follow-up visits.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Persona® SoluTion® PPS femoral implant (a knee replacement device)

What this could lead to

If successful, this could confirm that the implant improves knee function and reduces pain for people with arthritis or knee damage.

What could go wrong

This is a post-market study, not a new treatment. Results may not apply to all patients, and risks like infection or implant failure remain possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

arthritic joint disease Collagen Diseases disease osteoarthritis, knee polyarticular arthritis rheumatic disorder rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AVASCULAR NECROSIS OF FEMORAL CONDYLE COLLAGEN DISORDERS FLEXION DEFORMITY OF KNEE OSTEO ARTHRITIS OF THE KNEE POLYARTHRITIS RHEMATOID ARTHRITIS TRAUMATIC ARTHRITIS OF KNEE (DIAGNOSIS) VALGUS DEFORMITY VARUS DEFORMITY

Contacts and locations

Locations

  • Denver Hip and Knee, Inc.

    Denver, Colorado, 80134, United States