New knee implant tested for better mobility and less pain

NCT ID NCT07286513

ENROLLING_BY_INVITATION Disease control Sponsor: Zimmer Biomet Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 09, 2026 · Updated 3 times

Summary

This study is testing a new knee implant called the Persona SoluTion PPS femur in 200 adults who need total knee replacement. The goal is to see if it safely improves knee function and reduces pain over two years. Participants will have their knee health measured before surgery and at follow-up visits.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Persona® SoluTion® PPS femoral implant (a knee replacement device)
What this could lead to
If successful, this could confirm that the implant improves knee function and reduces pain for people with arthritis or knee damage.
What could go wrong
This is a post-market study, not a new treatment. Results may not apply to all patients, and risks like infection or implant failure remain possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Denver Hip and Knee, Inc.

    Denver, Colorado, 80134, United States

  • Medstar Health Research Institute

    Baltimore, Maryland, 21218, United States

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