Can scans and blood predict CAR T-Cell success?

NCT ID NCT05422521

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study looked at whether special scans (18FDG PET-CT) and blood tests could help predict how well CAR T-cell therapy works for people with hard-to-treat non-Hodgkin's lymphoma. Twenty patients were followed for up to a year after treatment. The goal was to see if these tests could spot early signs of the cancer coming back or severe side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
18FDG PET-CT scans and blood samples
What this could lead to
If successful, this could help doctors predict how well CAR T-cell therapy works for lymphoma patients and identify side effects earlier.
What could go wrong
This is a very small pilot study with only 20 participants, so results may not apply to everyone. It is exploratory and does not test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU de Nice

    Nice, 06000, France