New drug combo may calm painful blisters in elderly skin disease

NCT ID NCT04563923

First seen Mar 26, 2026 · Last updated May 16, 2026 · Updated 7 times

Summary

This study tested whether adding avdoralimab (an antibody that blocks a specific immune signal) to strong steroid creams helps people with bullous pemphigoid, a blistering skin disease common in people over 70. Fifteen participants received the combination, and researchers measured how many achieved complete remission without relapse at 3 months. The goal is to find a safer, more targeted treatment that reduces reliance on steroids.

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Contacts and locations

Locations

  • APHM, Hôpital Nord

    Marseille, Bouches du rhône, 13000, France

  • APHM, Timone

    Marseille, Bouche Du Rhône, 13005, France

  • CHU Montpellier, Dermatologie

    Montpellier, Herault, 34005, France

  • CHU de Nice- Dermatologie

    Nice, Alpes-Maritimes, 06200, France

Conditions

Explore the condition pages connected to this study.