Brain scans reveal how nerve stimulation may tame cluster headaches
NCT ID NCT02081482
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at 20 people with hard-to-treat chronic cluster headache who were already receiving occipital nerve stimulation. Researchers used brain scans to see how the stimulation changes brain activity. The goal was to understand how the treatment works, not to test if it works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
occipital nerve stimulation (a device that sends electrical pulses to nerves at the back of the head)
What this could lead to
If successful, this could reveal how occipital nerve stimulation changes brain activity, pointing toward better treatments for cluster headache.
What could go wrong
This is a very small, early-stage study focused on understanding the mechanism, not on proving the treatment works. Results may not apply to everyone.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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CHU -Hôpital Gabriel Montpied
Clermont-Ferrand, 63000, France
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Centre d'Urgence Céphalées
Paris, 75010, France
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Département d'Evaluation et Traitement de la Douleur - Pôle Neurosciences Cliniques - Centre Hospitalo-Universitaire de Nice
Nice, 06000, France
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Institut des Neurosciences
Marseille, 13385, France