Could a probiotic tame your canker sores?
NCT ID NCT02789605
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a probiotic called Lactobacillus rhamnosus Lcr35® can reduce the number of painful canker sores in people who get them often. Twenty adults with frequent outbreaks took either the probiotic or a placebo daily for 3 months, then were monitored for another 3 months. The goal was to see if the probiotic could safely lower the number of sores and improve quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Lactobacillus rhamnosus Lcr35® (a probiotic)
- What this could lead to
- If it works, this could point toward a simple, safe probiotic treatment to reduce canker sore outbreaks.
- What could go wrong
- This is a very small, early-phase trial (20 participants) with no published results yet. The benefit may be small or no better than placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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CHU de NIce - Dermatologie
Nice, Alpes-Maritimes, 06200, France