Green tea cream shows promise for rare 'Fish Scale' skin disease

NCT ID NCT01222000

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a cream made from green tea extract (Veregen) on 6 people with lamellar ichthyosis, a rare genetic condition that causes severe dry, scaly skin. Participants applied the cream to one side of their body and a standard moisturizer to the other for 4 weeks. The goal was to see if the green tea cream could improve skin scaling and roughness better than moisturizer alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

green tea extract (epigallocatechin-3-gallate) cream

What this could lead to

If it works, this could point toward a new topical treatment to ease skin scaling and roughness in lamellar ichthyosis.

What could go wrong

This is a very small pilot study with only 6 participants, so results may not apply to everyone. The treatment is tested on just one side of the body, and it may not work or may cause skin irritation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

autosomal recessive congenital ichthyosis 1 lamellar ichthyosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Service de dermatologie CHU de Nice

    Nice, France

  • Toulouse University Hospital, Dermatology Department

    Toulouse, France