Scientists test new ways to deliver vaccines through nose and mouth
NCT ID NCT00820144
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase study in 40 healthy adults explores how the immune system reacts to the non-toxic part of cholera toxin (CTB) when given through the nose, mouth, or under the tongue. The goal is to understand mucosal immune responses, which could help in developing future vaccines that are easier to take. No direct benefit is expected for participants.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cholera toxin B-subunit (CTB)
What this could lead to
If successful, this research could help design better vaccines that are given through the nose or mouth instead of by injection.
What could go wrong
This is a very early, small study with only 40 healthy volunteers. It is not testing a treatment or vaccine, just measuring immune responses, so it may not lead to any practical application.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Laboratoire d'anatomo-pathologie, hôpital Pasteur
Nice, 06000, France