Kidney transplant drug dosing gets a closer look

NCT ID NCT01435291

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at how the drug Advagraf (a form of tacrolimus) works in 45 adults who received a kidney transplant. The goal was to find better ways to dose the drug by measuring its levels in the blood right after transplant and three months later. Researchers compared Advagraf with another version of the same drug called Prograf.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Advagraf (tacrolimus prolonged release)

What this could lead to

If successful, this could help doctors give more precise doses of Advagraf to kidney transplant patients, potentially reducing side effects and improving outcomes.

What could go wrong

This is a small, completed pharmacokinetic study, not a large trial testing a new treatment. The findings may not change standard practice or apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHRU Tours Hôpital Bretonneau

    Tours, France

  • CHU de Nice

    Nice, 06200, France

  • CHU de Rangueil

    Toulouse, France

  • Hôpital Bicêtre

    Le Kremlin-Bicêtre, France