New study tracks immune cell function after stem cell transplants to personalize care

NCT ID NCT04635397

Completed Knowledge-focused Sponsor: Centre Hospitalier Universitaire de Nice Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at how immune cells recover in 61 adults who received a stem cell transplant for blood cancers. Researchers measured the function of T and NK cells by testing their cytokine profiles after stimulation. The goal was to see if these measurements could help predict and manage complications like infections, relapse, and graft-versus-host disease (GvHD).

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors personalize post-transplant care by adjusting immune-suppressing drugs or anti-infection treatments based on a patient's immune recovery.
What could go wrong: This is an observational study, not a treatment trial. It aims to gather information, not test a new therapy, so it won't directly improve outcomes for participants.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute leukemia hematopoietic and lymphoid cell neoplasm myelodysplastic syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEMATOPOIETIC STEM CELL TRANSPLANTATION

Contacts and locations

Locations

CHU de Nice

Nice, CHU de NICE, 06003, France

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