Can brain tests predict who will beat stubborn depression?
NCT ID NCT02774980
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at 30 adults aged 40-70 with treatment-resistant depression to see if changes in thinking skills (like memory and attention) could predict when depression improves. Researchers measured mood, daily function, and cognitive abilities before and after starting a new antidepressant, then again at 6 and 12 months. The goal was to find mental markers that help doctors choose better treatments for people who haven't gotten relief from standard therapies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help doctors predict which depression treatments will work for patients who haven't responded to previous therapies.
What could go wrong
This is a small, observational study with only 30 participants. It does not test a new treatment, so it may not lead to immediate changes in care.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hopital Pasteur
Nice, 06000, France