Which fluid works best for severe diabetic ketoacidosis? a new trial aims to find out
NCT ID NCT06541535
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two types of IV fluids—saline and Ringer lactate—in 300 adults with severe diabetic ketoacidosis (DKA) admitted to the ICU. The goal is to see which fluid helps resolve DKA faster within 24 hours. Current guidelines recommend saline, but it may cause side effects; Ringer lactate has a more balanced composition and might work better.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU NICE
RECRUITINGNice, France