Could a common mental health drug prevent weight loss in cancer patients?

NCT ID NCT07633236

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a low dose of olanzapine, a drug usually used for mental health conditions, can prevent or treat the loss of appetite and weight that often happens in cancer patients receiving chemotherapy. About 100 adults with stomach or ovarian cancer will take the drug daily during their pre-surgery chemo. The goal is to see if it helps them maintain weight, control nausea, and feel better overall.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

olanzapine (a drug typically used for mental health conditions, here at a low dose)

What this could lead to

If it works, this could offer a simple, low-cost way to help cancer patients maintain weight and quality of life during chemotherapy.

What could go wrong

This is a single-center trial with only 100 participants, so results may not apply broadly. Olanzapine can cause side effects like drowsiness or metabolic changes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gastric cancer neoplasm ovarian cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Federal State Budgetary Institution "N.N. Blokhin National Medical Research Center of Oncology" оf the Ministry of Health of the Russian Federation

    RECRUITING

    Moscow, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••