The Hospital For Sick Children
Clinical trials sponsored by The Hospital For Sick Children, explained in plain language.
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Can changing a Child's diet tame arthritis? new study investigates gut connection
Disease control Recruiting nowThis study is exploring whether following a Mediterranean-style diet for 8-12 weeks can help reduce disease activity in children with juvenile arthritis. Researchers want to see if dietary changes improve symptoms by altering the community of bacteria in the gut (the microbiome).…
Phase: NA • Sponsor: The Hospital for Sick Children • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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SickKids tests AI to predict which heart patients need extra help
Disease control Recruiting nowThis study is testing whether a computer program can help doctors identify children in the hospital with serious heart conditions who are at high risk of a major health event. The program predicts which patients might benefit from earlier conversations with a special support team…
Phase: NA • Sponsor: The Hospital for Sick Children • Aim: Disease control
Last updated Mar 13, 2026 15:05 UTC
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Common diabetes drug tested as potential brain repair treatment for young MS patients
Disease control Recruiting nowThis early-stage study is testing whether metformin, a common diabetes medication, can help the brain repair itself in children and young adults with multiple sclerosis (MS). Researchers will give the drug to 20 participants and closely monitor its safety and how well it's tolera…
Phase: PHASE1, PHASE2 • Sponsor: The Hospital for Sick Children • Aim: Disease control
Last updated Mar 12, 2026 13:52 UTC
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New breath-hold scan aims to spot hidden lung damage in transplant kids
Diagnosis Recruiting nowThis study is testing if a special type of MRI scan, where children hold their breath while inhaling a safe gas, can help doctors spot a serious lung condition earlier. The condition, called bronchiolitis obliterans syndrome, can happen after a child receives a stem cell transpla…
Sponsor: The Hospital for Sick Children • Aim: Diagnosis
Last updated Apr 01, 2026 20:11 UTC
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Breakthrough scans aim to spot lung damage earlier
Diagnosis Recruiting nowThis study is testing two new types of MRI scans that use safe, inhaled gases instead of radiation to create detailed pictures of the lungs. Researchers want to see if these scans can detect changes in lung structure and function in people with cystic fibrosis or asthma more clea…
Phase: PHASE2 • Sponsor: The Hospital for Sick Children • Aim: Diagnosis
Last updated Mar 19, 2026 14:56 UTC
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AI steps in to stop sick Kids' chemo vomiting
Symptom relief Recruiting nowThis study tests whether a computer model can predict which children in the hospital for cancer treatment are most likely to vomit in the next four days. If the model flags a child as high-risk, pharmacists will alert the medical team so they can start preventive anti-nausea medi…
Phase: NA • Sponsor: The Hospital for Sick Children • Aim: Symptom relief
Last updated Apr 01, 2026 14:43 UTC
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New hope to stop Kids' chemo sickness
Symptom relief Recruiting nowThis study is testing if adding a drug called olanzapine to standard anti-nausea medicines can better control vomiting in children receiving very strong chemotherapy for cancer or before a stem cell transplant. It will involve about 200 children and teenagers. The main goal is to…
Phase: PHASE2 • Sponsor: The Hospital for Sick Children • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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AI steps in to personalize Kids' cancer drug doses
Knowledge-focused Recruiting nowThis study is testing whether a computer model can help doctors identify children in the hospital who are likely to need certain medications soon, so that genetic testing can be offered in advance. The goal is to see if this timely testing leads to more personalized medication ch…
Phase: NA • Sponsor: The Hospital for Sick Children • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:28 UTC
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Scientists track how kids spread colds and flu at home and school
Knowledge-focused Recruiting nowThis study aims to better understand how common respiratory viruses like the flu, RSV, and COVID-19 spread among children. Researchers will track 500 children under 18 who test positive for one of these viruses, along with their household and classroom contacts. The goal is to le…
Sponsor: The Hospital for Sick Children • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:42 UTC