Brain pacemaker trial aims to stop Self-Harm in kids with autism

NCT ID NCT06529380

Recruiting now Disease control Sponsor: The Hospital for Sick Children Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests whether deep brain stimulation (DBS) of the nucleus accumbens can reduce severe, repetitive self-injurious behaviors in 25 children aged 5-17 with autism. Half will get active stimulation, half will have the device off, and parents will report behavior changes. The goal is to see if DBS can control these dangerous behaviors when other treatments have not worked.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: deep brain stimulation (DBS) of the nucleus accumbens
What this could lead to: If it works, this could offer a new way to control severe self-injurious behaviors in children with autism when other treatments have failed.
What could go wrong: This is a small, early-stage trial with only 25 children. DBS involves brain surgery, which carries risks like infection or bleeding. It may not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

autism spectrum disorder Self-Injurious Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AUTISM SPECTRUM DISORDER SELF-INJURIOUS BEHAVIOR

Contacts and locations

Locations

The Hospital for Sick Children
RECRUITING

Toronto, Ontario, M5G1X8, Canada

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