Brain pacemaker trial aims to stop Self-Harm in kids with autism

NCT ID NCT06529380

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests whether deep brain stimulation (DBS) of the nucleus accumbens can reduce severe, repetitive self-injurious behaviors in 25 children aged 5-17 with autism. Half will get active stimulation, half will have the device off, and parents will report behavior changes. The goal is to see if DBS can control these dangerous behaviors when other treatments have not worked.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

deep brain stimulation (DBS) of the nucleus accumbens

What this could lead to

If it works, this could offer a new way to control severe self-injurious behaviors in children with autism when other treatments have failed.

What could go wrong

This is a small, early-stage trial with only 25 children. DBS involves brain surgery, which carries risks like infection or bleeding. It may not work for everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

autism spectrum disorder Self-Injurious Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Hospital for Sick Children

    RECRUITING

    Toronto, Ontario, M5G1X8, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••