The Hospital For Sick Children

This study looks at whether a non-invasive technique called focused ultrasound can safely treat brain lesions that cause seizures in 20 children aged 4-17 with drug-resistant epilepsy. The goal is to reduce seizure frequency and severity, and improve quality of life. Participants…

This study tests a program called ONLOOP that sends reminders to adult survivors of childhood cancer in Ontario to get important screening tests. These tests can find late effects like heart disease or second cancers early. About 900 survivors will be randomly assigned to receive…

This study looks at whether a mechanical arm ultrasound system can find joint damage in people with hemophilia as well as a full expert ultrasound or MRI. Eleven participants will get both types of scans to compare accuracy. If successful, this simpler method could catch early jo…

This study tests a smartphone app called PainCaRe that gives parents real-time advice on managing their young child's cancer pain at home. About 40 parents of children aged 2-11 with cancer will use the app for 8 weeks. The goal is to see if the app is easy to use and helps reduc…

This study explores whether MRI can create detailed images of the lungs and airways in children and teens with cystic fibrosis (CF) and healthy volunteers. Researchers will use computer assistance to measure airway size and shape, and repeat scans after two years to track changes…

This pilot study aims to see if a larger clinical trial comparing dexamethasone to a placebo for children hospitalized with orbital cellulitis is possible. Researchers will check if they can recruit enough patients, give the treatment correctly, and collect all needed data. The s…

This study is testing a smartphone app called MedlyPeds that lets children with heart disease and their families report symptoms and health data from home. About 30 kids aged 8-18 will use the app for 3 months. The goal is to see if the app is easy to use and helpful, and to get …

This study looks at whether you need to eat complementary plant proteins—like rice and beans—at the same meal to get all the amino acids your body needs. Researchers will compare protein metabolism when proteins are combined in one meal versus spread out over the day. The study i…

This study compares AI-assisted video laryngoscopy to standard video laryngoscopy for placing breathing tubes in children and newborn mannequins. Forty healthcare workers with different experience levels will perform intubations to see if AI guidance speeds up the process and imp…

This study looks at whether the location of the anesthesia machine in the operating room affects how well anesthesiologists manage a crisis and perform life-saving tasks like giving breaths with a bag and mask. About 60 doctors will take part in a simulated emergency using a mani…