The Hospital For Sick Children
Clinical trials sponsored by The Hospital For Sick Children, explained in plain language.
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Could iron boosts sharpen Toddlers' minds? new study investigates
Disease control CompletedThis study looked at whether giving iron supplements to children aged 1 to 3 years with low iron (but not full anemia) helps their brain development. 127 children received either iron liquid or a placebo for 4 months, plus diet advice. Researchers measured learning skills before …
Phase: NA • Sponsor: The Hospital for Sick Children • Aim: Disease control
Last updated May 16, 2026 23:53 UTC
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Texting teens with diabetes: can a simple message boost confidence?
Disease control CompletedThis study tested whether personalized text messages can help young adults with type 1 diabetes feel more confident managing their condition as they move from pediatric to adult care. 234 participants received either usual care or usual care plus text message support. The goal wa…
Phase: NA • Sponsor: The Hospital for Sick Children • Aim: Disease control
Last updated May 13, 2026 15:58 UTC
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New tool helps kids with cancer feel better during treatment
Symptom relief CompletedThis study tested a program that asks children with cancer about their symptoms three times a week and then gives doctors guidelines to manage those symptoms. The goal was to see if this approach reduces bothersome symptoms and improves quality of life. The study involved 445 chi…
Phase: NA • Sponsor: The Hospital for Sick Children • Aim: Symptom relief
Last updated May 16, 2026 23:46 UTC
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Online buddies ease caregiver burden in rare disease study
Symptom relief CompletedThis study tested whether virtual peer support helps family caregivers of people with neuromuscular disease feel more in control and less isolated. About 100 Canadian caregivers joined online sessions with trained peer mentors who also care for someone with the same condition. Th…
Phase: NA • Sponsor: The Hospital for Sick Children • Aim: Symptom relief
Last updated May 11, 2026 20:47 UTC
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New app helps teens take control of chronic pain
Symptom relief CompletedThis study tested a smartphone app and website called ICanCope with Pain for teens and young adults aged 15-25 who have chronic pain. The program helps users track pain, sleep, mood, and activity, set goals, and learn pain management skills. Researchers checked if the program was…
Phase: NA • Sponsor: The Hospital for Sick Children • Aim: Symptom relief
Last updated May 07, 2026 18:41 UTC
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Supplements and exercise show promise for kids with muscle disease
Symptom relief CompletedThis study looked at whether taking creatine and coenzyme Q10 supplements, along with exercise, could help children with juvenile myositis build muscle strength and reduce fatigue. Fifteen children aged 7 to 18 participated. The goal was to see if these supplements could give mus…
Phase: NA • Sponsor: The Hospital for Sick Children • Aim: Symptom relief
Last updated May 07, 2026 18:40 UTC
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Hemophilia treatment showdown: which therapy makes life better for boys?
Knowledge-focused CompletedThis study looked at how different preventive treatments for moderate or severe hemophilia A affect the daily lives of boys aged 7 to 18 and their families. Researchers compared an intravenous factor replacement product with a subcutaneous non-factor product by having participant…
Sponsor: The Hospital for Sick Children • Aim: Knowledge-focused
Last updated May 16, 2026 23:49 UTC
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Healthy adult study paves way for safer nutrition in preterm babies
Knowledge-focused CompletedThis study involved 10 healthy adults to develop a method for measuring how the body breaks down tryptophan, an essential amino acid. The goal is to later apply this method to preterm babies receiving IV nutrition, where too much tryptophan can produce harmful brain compounds. Pa…
Phase: NA • Sponsor: The Hospital for Sick Children • Aim: Knowledge-focused
Last updated May 16, 2026 23:38 UTC
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Virtual program aims to ease tough transition to home breathing machines
Knowledge-focused CompletedThis study tested whether a virtual support program helps people who need a breathing machine at home transition more smoothly. 444 adults and children in Ontario took part. The program used online tools to connect patients and caregivers with healthcare teams, aiming to reduce e…
Phase: NA • Sponsor: The Hospital for Sick Children • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Oxygen boost for moms may protect fetal brains in heart defect cases
Knowledge-focused CompletedThis study looked at whether giving pregnant mothers extra oxygen can increase oxygen levels in the brains of fetuses with congenital heart disease. Researchers used MRI and ultrasound to measure changes in 53 fetuses. The goal is to find out if this approach could one day be use…
Phase: NA • Sponsor: The Hospital for Sick Children • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Inflammation markers studied in kids with heart defects and lung hypertension
Knowledge-focused CompletedThis study looked at whether a specific inflammatory protein, HMGB1, is higher in children with congenital heart disease and pulmonary hypertension compared to those with heart disease alone or healthy children. Researchers measured blood samples from 74 children during heart cat…
Sponsor: The Hospital for Sick Children • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC