The Hospital For Sick Children

This study tested a simple scoring system called RISQ to help healthcare workers quickly identify which severely malnourished children are most at risk of dying. Over 14,600 children aged 6 to 59 months in Chad took part. The goal was to see if using the RISQ system could lower d…

This study tested whether a mindfulness program could help teenagers with obstructive sleep apnea use their CPAP machine more regularly. 37 teens aged 13-18 with moderate to severe sleep apnea took part. The program taught skills like awareness and resilience, and the researchers…

This study tested whether a short course of the steroid dexamethasone can reduce the severity of obstructive sleep apnea in children aged 2 to 10. Ten children with moderate-to-severe sleep apnea received either the drug or a placebo for three days. The goal was to see if the ste…

This study tested whether virtual peer support helps family caregivers of people with neuromuscular disease feel more in control and less isolated. About 100 Canadian caregivers joined online sessions with trained peer mentors. The goal was to improve caregivers' sense of mastery…

This study tested whether personalized text messages could help young adults with type 1 diabetes feel more confident managing their condition as they moved from pediatric to adult care. 234 participants received either usual care or usual care plus a text messaging program. The …

This study looked at whether taking creatine and coenzyme Q10 supplements, along with exercise, could help children with juvenile myositis (a disease that causes muscle weakness and fatigue). Fifteen children aged 7 to 18 took part. The goal was to see if these supplements could …

This study tested a smartphone app and website called iCanCope with Pain, designed to help teens and young adults (ages 15-25) manage chronic pain. The app lets users track pain, sleep, mood, and activity, set goals, and learn coping strategies. The goal was to see if the program…

This study tested whether having children with cancer report their symptoms three times a week using a web-based tool (SPARK) could improve their quality of life. The tool alerted healthcare providers and linked to care pathways for managing symptoms. A total of 445 children aged…

This study measured levels of an inflammatory protein called HMGB1 in 74 children with congenital heart disease and pulmonary hypertension. Researchers compared these levels to those in children with heart disease alone and healthy controls. The goal was to see if inflammation pl…

This study looked at whether giving extra oxygen to pregnant mothers carrying babies with congenital heart disease (CHD) could increase oxygen levels in the fetal brain. Researchers used ultrasound and MRI to measure changes in 53 fetuses with different types of CHD. The goal was…

This study looked at whether giving extra oxygen to pregnant women can help doctors tell how well blood mixes in the hearts of unborn babies with a condition called transposition of the great arteries (TGA). Researchers used ultrasound and MRI to measure blood flow and heart stru…

This completed observational study looked at boys aged 7-18 with moderate or severe hemophilia A in Canadian treatment centres. Researchers compared quality of life and caregiver burden between those receiving an intravenous factor replacement product and those on a subcutaneous …

This study aims to develop a method to measure how the body breaks down tryptophan, an essential amino acid. Ten healthy adults aged 18-45 will take a special tracer and provide blood and urine samples. The goal is to later use this method to improve nutrition for preterm babies …

This study tested a virtual support program for 444 people starting home ventilation. The program used online tools to help patients and caregivers manage care at home. Researchers measured if it reduced emergency room visits and eased caregiver stress compared to usual care.

This study looked at whether finding and treating low iron (without anemia) in children aged 1 to 3 years can improve their early learning skills like language and motor abilities. About 127 children had a blood test, and those with low iron were given either iron liquid or a pla…