Can a simple kit cut newborn deaths by 25%? a major trial in pakistan aims to find out
NCT ID NCT04798833
First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time
Summary
This trial tests whether an integrated newborn care kit (iNCK) can reduce deaths in the first month of life. The kit includes clean birth supplies, misoprostol to prevent severe bleeding after delivery, chlorhexidine for umbilical cord care, sunflower oil emollient, and a temperature monitor. Nearly 20,000 pregnant women in rural Gilgit-Baltistan, Pakistan, will receive the kit or standard care to see if it lowers neonatal mortality by at least 25%.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- An integrated newborn care kit containing a clean birth kit, misoprostol tablets, chlorhexidine solution, sunflower oil emollient, and a temperature monitor
- What this could lead to
- If effective, this simple kit could prevent thousands of newborn deaths and improve maternal health in regions with limited access to medical care.
- What could go wrong
- The trial is large but relies on community health workers for distribution and proper use, which may affect results. Misoprostol carries risks if not taken correctly.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Aga Khan Health Services, Pakistan
Islamabad, Pakistan
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Aga Khan University
Karachi, Pakistan
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