The Hospital For Sick Children
Clinical trials sponsored by The Hospital For Sick Children, explained in plain language.
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Could a blood pressure cuff save Babies' lives? new trial tests simple treatment for devastating bowel disease
Disease control OngoingThis study is testing if a simple, non-invasive procedure called remote ischemic conditioning (RIC) can help treat a serious intestinal disease in newborns called necrotizing enterocolitis (NEC). The procedure involves inflating and deflating a blood pressure cuff on the baby's a…
Phase: PHASE2 • Sponsor: The Hospital for Sick Children • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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ER program aims to clear Kids' false allergy labels
Disease control ENROLLING_BY_INVITATIONThis study is testing a program in a children's emergency department that safely removes inaccurate antibiotic allergy labels from kids' medical records. Many children are mistakenly labeled as allergic to common antibiotics like penicillin or amoxicillin, often due to rashes tha…
Phase: PHASE1 • Sponsor: The Hospital for Sick Children • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Spit test for strep? study aims to replace uncomfortable throat swabs for kids
Diagnosis OngoingThis study is testing whether a simple saliva sample can be used to diagnose strep throat, instead of the standard throat swab. Researchers are enrolling up to 200 children and teenagers to compare the accuracy of saliva testing against throat swab testing. The goal is to find a …
Phase: NA • Sponsor: The Hospital for Sick Children • Aim: Diagnosis
Last updated Apr 01, 2026 14:43 UTC
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New hope for teens in crisis: emergency department program aims to stop suicide
Prevention OngoingThis study is testing whether a special 6-week program can help prevent suicide attempts in teenagers who come to the emergency room with suicidal thoughts or behaviors. The program teaches teens skills to manage suicidal thoughts and helps families improve communication. Researc…
Phase: NA • Sponsor: The Hospital for Sick Children • Aim: Prevention
Last updated Mar 27, 2026 12:41 UTC
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Can an app get inactive teens with MS moving?
Symptom relief OngoingThis study is testing a smartphone app designed to help teens with multiple sclerosis (MS) become more physically active. The app provides coaching and tools to set goals and connect with others. Researchers want to see if using the app increases activity levels and improves qual…
Phase: NA • Sponsor: The Hospital for Sick Children • Aim: Symptom relief
Last updated Mar 31, 2026 12:12 UTC
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MRI scans could offer new window into cystic fibrosis treatment effects
Knowledge-focused OngoingThis study aims to see if MRI scans can detect changes in the lungs of people with cystic fibrosis who are receiving new CFTR-modulator treatments. Researchers will compare MRI results to standard breathing tests and quality of life measures over several years. The study includes…
Sponsor: The Hospital for Sick Children • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Scientists measure how well our bodies use corn protein
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to measure how well healthy adults over 60 absorb a specific protein component (tryptophan) from cooked cornmeal. Researchers will feed participants controlled diets with corn and collect breath samples to see how much of this nutrient the body retains. The goal i…
Phase: NA • Sponsor: The Hospital for Sick Children • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC