MRI scans could reveal hidden lung changes in kids with cystic fibrosis

NCT ID NCT04391322

First seen Feb 27, 2026 · Last updated May 23, 2026 · Updated 11 times

Summary

This study tests whether MRI scans can detect lung changes in people with cystic fibrosis (CF) who take CFTR-modulator drugs. About 86 participants, including healthy volunteers and CF patients aged 4 and older, will have multiple MRI scans and breathing tests over up to 3 years. The goal is to see if MRI is a better tool than standard tests for tracking how well the medication works.

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Contacts and locations

Locations

  • The Hospital for Sick Children

    Toronto, Ontario, M5G 1X8, Canada

Conditions

Explore the condition pages connected to this study.