Could a blood pressure cuff save tiny lives? new trial explores simple treatment for deadly newborn gut disease

NCT ID NCT05279664

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at a procedure called remote ischemic conditioning (RIC) for newborns with necrotizing enterocolitis (NEC), a serious gut disease. RIC involves briefly inflating a blood pressure cuff on the baby's arm to protect the gut from damage. The main goal is to see if a larger, more definitive trial is possible, so it focuses on how many families agree to join and how well the procedure can be masked. About 78 babies will take part to test the feasibility of this approach.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Mount Sinai Hospital

    Toronto, Ontario, M5G 1X5, Canada

  • Sunnybrook Health Sciences Center

    Toronto, Ontario, M4Y 3M5, Canada

  • The Hospital for Sick Children

    Toronto, Ontario, M5G1X8, Canada

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Other studies related to the condition(s) this trial covers.