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Gut bacteria clues could help predict dangerous bowel disease in preemies

NCT ID NCT04972734

Completed Knowledge-focused Sponsor: University Hospital, Clermont-Ferrand Source: ClinicalTrials.gov ↗

First seen Jul 10, 2026 · Last updated Jul 10, 2026

Summary

This study looks at the gut bacteria of premature babies to see if differences exist between those who develop necrotizing enterocolitis (NEC) — a severe bowel condition — and those who do not. Researchers collect weekly blood and daily stool samples from about 300 premature infants over 12 weeks. The goal is to better understand the role of gut microbes in NEC, which could eventually help with early detection or prevention.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If differences in gut bacteria are found, this could lead to earlier detection or prevention of NEC in premature babies.
What could go wrong
This is an observational study, not a treatment trial. It may not identify clear bacterial patterns, and any findings will need further research to become useful.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

necrotizing enterocolitis Premature Birth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NECROTIZING ENTEROCOLITIS PREMATURE BIRTH

Contacts and locations

Locations

  • CHU Clermont-Ferrand

    Clermont-Ferrand, France

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