Can Oxygen-Sensing MRI help personalize childhood cancer treatment?
NCT ID NCT03054792
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether special MRI scans can measure oxygen levels inside children's sarcoma tumors. Low oxygen (hypoxia) can make tumors harder to treat. The scans are done before and after standard chemotherapy or radiation to see if they can predict how well the tumor responds. If the approach works, it may one day help doctors personalize treatment for each child.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors tailor chemotherapy and radiation for each child with sarcoma, potentially improving outcomes.
- What could go wrong
- This is a very small, early feasibility study (18 participants) focused on imaging, not treatment. The techniques may not prove reliable enough to change clinical practice.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The Hospital for Sick Children
Toronto, Ontario, M5G 1X8, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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