Breathing in a new view: lung MRI study aims to see inside without X-Rays

NCT ID NCT02740868

Recruiting now Knowledge-focused Sponsor: The Hospital for Sick Children Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing two new types of lung MRI that use special gases (xenon and perfluoropropane) to create detailed images of lung function. Researchers will compare these scans in 30 people with cystic fibrosis, asthma, and healthy volunteers to see if they can spot lung problems earlier and more clearly than standard tests. The goal is to develop a safer, radiation-free way to monitor lung disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Xenon-129 and perfluoropropane gas (inhaled)
What this could lead to: If successful, this could lead to a new, radiation-free way to monitor lung disease in children and adults with cystic fibrosis or asthma.
What could go wrong: This is a small pilot study with only 30 participants, so results may not apply to everyone. The new MRI methods may not prove better than existing tests.

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Conditions

The condition(s) this trial relates to.

asthma cystic fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTHMA CYSTIC FIBROSIS

Contacts and locations

Locations

The Hospital for Sick Children
RECRUITING

Toronto, Ontario, M5G 1X8, Canada

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