Live biopsy study aims to predict immunotherapy response in cancer patients

NCT ID NCT07327489

Recruiting now Knowledge-focused Sponsor: Elephas Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times

Summary

This study is collecting live tumor samples from 2,000 cancer patients undergoing standard biopsies. Researchers will analyze these samples to understand how tumors respond to immunotherapy drugs outside the body. The goal is to develop a method to predict which patients will respond to treatment, potentially saving time and reducing side effects from ineffective therapies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could lead to a test that helps doctors predict which patients will benefit from immunotherapy, avoiding ineffective treatments.
What could go wrong: This is an observational study, not a treatment trial. It is early-stage research, and the findings may not translate into a reliable clinical test for years, if at all.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer colorectal cancer colorectal neoplasm endometrial cancer endometrium neoplasm head and neck cancer Head and Neck Neoplasms kidney cancer liver cancer Liver Neoplasms Lynch syndrome melanoma neoplasm non-small cell lung carcinoma skin cancer skin neoplasm triple-negative breast carcinoma urinary bladder carcinoma Urinary Bladder Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADVANCED SOLID TUMORS CANCER BLADDER CANCER CANCER COLORECTAL CANCER DMMR COLORECTAL CANCER ENDOMETRIAL CANCER HEAD AND NECK CANCER IMMUNOTHERAPY KIDNEY CANCER LIVER CANCER MELANOMA (SKIN CANCER) MSI-H COLORECTAL CANCER NSCLC (NON-SMALL CELL LUNG CANCER) SKIN CANCER TNBC - TRIPLE-NEGATIVE BREAST CANCER

Contacts and locations

Locations

Baylor Scott and White Biorepository
NOT_YET_RECRUITING

Temple, Texas, 76508, United States
Frederick Health Hospital
RECRUITING

Frederick, Maryland, 21702, United States
JPS Health Network
RECRUITING

Forth Worth, Texas, 76104, United States
Mercy Hospital - FTS
RECRUITING

Fort Smith, Arkansas, 72903, United States
Mercy Hospital - OKC
RECRUITING

Oklahoma City, Oklahoma, 73120, United States
Mercy Hospital - SPG
RECRUITING

Springfield, Missouri, 65804, United States
Mercy Hospital - South
RECRUITING

St Louis, Missouri, 63128, United States
Mercy Hospital -STL
RECRUITING

St Louis, Missouri, 63141, United States

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