Inhaled drug could stop deadly lung bleeding in cancer patients

NCT ID NCT05053867

Recruiting now Disease control Sponsor: M.D. Anderson Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 17, 2026 · Updated 3 times

Summary

This study tests whether inhaling a drug called tranexamic acid can help stop lung bleeding in cancer patients who are on breathing machines. The trial includes 60 adults with blood cancers and severe lung bleeding. Half will get the inhaled drug plus usual care, and half will get usual care alone. The main goal is to see if more patients are alive 28 days later.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: tranexamic acid (inhaled)
What this could lead to: If it works, this could provide a new way to control severe lung bleeding in cancer patients, potentially saving lives in the intensive care unit.
What could go wrong: This is a small early-phase trial with only 60 participants, so results may not apply broadly. The drug may not improve survival and could have side effects like blood clots.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer hematopoietic and lymphoid system neoplasm neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANCER PULMONARY HEMORRHAGE

Contacts and locations

Locations

M D Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States

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