Warm during surgery? new trial tests if temperature control boosts survival in older cancer patients

NCT ID NCT06256354

Recruiting now Disease control Sponsor: Peking University First Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether carefully managing body temperature during major cancer surgery can lower the risk of postoperative delirium (sudden confusion) and improve long-term survival in patients aged 65 and older. About 4,000 participants will be randomly assigned to either routine temperature care or active warming. The goal is to see if a simple, low-cost change in the operating room can make a real difference for older adults recovering from cancer surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: targeted temperature management (keeping body temperature stable during surgery)
What this could lead to: If it works, this simple approach could reduce confusion after surgery and help older cancer patients live longer.
What could go wrong: This is a large trial, but it tests a small change in routine care—benefits may be modest or not statistically significant. The results may not apply to all surgeries or patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer delirium Emergence Delirium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANCER SURGERY DELIRIUM HYPOTHERMIA INTRAOPERATIVE HYPOTHERMIA LONG-TERM SURVIVORS POSTOPERATIVE DELIRIUM TARGETED TEMPERATURE MANAGEMENT

Contacts and locations

Locations

Aerospace Medical Center
RECRUITING

Beijing, Beijing Municipality, China
Beijing Chao-Yang Hospital, Capital Medical University
NOT_YET_RECRUITING

Beijing, Beijing Municipality, China
Beijing Chuiyangliu Hospital
NOT_YET_RECRUITING

Beijing, Beijing Municipality, China
Beijing Coal Group General Hospital
NOT_YET_RECRUITING

Beijing, Beijing Municipality, China
Beijing Electric Power Hospital
RECRUITING

Beijing, Beijing Municipality, China
Chengdu Seventh People's Hospital
RECRUITING

Chengdu, Sichuan, 610041, China
Deyang People's Hospital
RECRUITING

Deyang, Sichuan, China
Dongzhimen Hospital Beijing University of Chinese Medicine
NOT_YET_RECRUITING

Beijing, Beijing Municipality, 100007, China
First Affiliated Hospital of Harbin Medical University
RECRUITING

Harbin, Heilongjiang, 163711, China
Guang'anmen Hospital China Academy of Chinese Medical Sciences
RECRUITING

Beijing, Beijing Municipality, 100055, China
Henan Provincial People's Hospital
NOT_YET_RECRUITING

Zhengzhou, Henan, 463599, China
Jiangsu Province Hospital
RECRUITING

Nanjing, Jiangsu, 210029, China
Jiangyin People's Hospital
RECRUITING

Jiangyin, Jiangsu, 214400, China
Jingzhou Central Hospital
NOT_YET_RECRUITING

Jingzhou, Hubei, China
Maanshan People's Hospital
RECRUITING

Ma’anshan, Anhui, China
Peking Union Medical College Hospital
RECRUITING

Beijing, Beijing Municipality, 100730, China
Peking University First Hospital
RECRUITING

Beijing, Beijing Municipality, 100034, China
Peking University International Hospital
NOT_YET_RECRUITING

Beijing, Beijing Municipality, China
Peking University Shenzhen Hospital
RECRUITING

Shenzhen, Guangdong, 518034, China
Sichuan Provincial People's Hospital
RECRUITING

Chengdu, Sichuan, 610072, China
The First Affiliated Hospital of Anhui Medical University
RECRUITING

Hefei, Anhui, 610042, China
The First Affiliated Hospital of Chengdu Medical College
RECRUITING

Chengdu, Sichuan, 610500, China
The First Affiliated Hospital of Chongqing Medical University
RECRUITING

Chongqing, Chongqing Municipality, China
The First Affiliated Hospital of Kangda College of Nanjing Medical University ( Lianyungang First People's Hospital)
NOT_YET_RECRUITING

Lianyungang, Jiangsu, China
The First Affiliated Hospital of Shandong First Medical University
NOT_YET_RECRUITING

Jinan, Shandong, 250013, China
The First Affiliated Hospital of Zhengzhou University
RECRUITING

Zhengzhou, Henan, 450052, China
The First Hospital of Tsinghua University
NOT_YET_RECRUITING

Beijing, Beijing Municipality, China
The Fourth Hospital of Hebei Medical University (Hebei Tumor Hospital)
NOT_YET_RECRUITING

Shijiazhuang, Hebei, 050011, China
The People's Hospital of Chizhou
NOT_YET_RECRUITING

Chizhou, Anhui, 247099, China
The People's Hospital of Liaocheng
RECRUITING

Liaocheng, Shandong, 252000, China
The People's Hospital of Wuxi
NOT_YET_RECRUITING

Wuxi, Jiangsu, 214023, China
The Second Affiliated Hospital of Anhui Medical University
RECRUITING

Hefei, Anhui, 230601, China
The Second Affiliated Hospital of Soochow University
NOT_YET_RECRUITING

Suzhou, Jiangsu, China
The Second People's Hospital of Yibin (affiliated with West China Hospital of Sichuan University)
NOT_YET_RECRUITING

Chengdu, Sichuan, China
Xijing Hospital, Fourth Military Medical University
RECRUITING

Xi'an, Shaanxi, 710032, China
Xiyuan Hospital of China Academy of Chinese Medical Sciences
RECRUITING

Beijing, Beijing Municipality, 100091, China

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