Cooling sleeve could shield cancer patients from chemo nerve pain

NCT ID NCT05606068

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a special cooling and compression sleeve (Paxman Limb Cryocompression System) worn during chemotherapy to prevent nerve damage, a common side effect. About 200 cancer patients receiving weekly paclitaxel will use the device for up to 4 hours per session. Researchers will check for side effects and measure changes in nerve symptoms using questionnaires.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Paxman Limb Cryocompression System (a cooling and compression sleeve)

What this could lead to

If it works, this could give cancer patients a way to prevent painful nerve damage from chemotherapy, improving their quality of life during and after treatment.

What could go wrong

This is an early expansion study with no control group, so results may not prove effectiveness. The device may cause discomfort or fail to prevent neuropathy in all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

cancer chemotherapy-induced neuropathy prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Curie Oncology, Mount Elizabeth Novena Specialist Centre

    NOT_YET_RECRUITING

    Singapore, 329563, Singapore

    Contact Phone: •••-•••-••••

    Contact

  • National University Hospital

    RECRUITING

    Singapore, 119074, Singapore

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact