Cooling sleeve could shield cancer patients from chemo nerve pain

NCT ID NCT05606068

Recruiting now Prevention Sponsor: National University Hospital, Singapore Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a special cooling and compression sleeve (Paxman Limb Cryocompression System) worn during chemotherapy to prevent nerve damage, a common side effect. About 200 cancer patients receiving weekly paclitaxel will use the device for up to 4 hours per session. Researchers will check for side effects and measure changes in nerve symptoms using questionnaires.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Paxman Limb Cryocompression System (a cooling and compression sleeve)
What this could lead to: If it works, this could give cancer patients a way to prevent painful nerve damage from chemotherapy, improving their quality of life during and after treatment.
What could go wrong: This is an early expansion study with no control group, so results may not prove effectiveness. The device may cause discomfort or fail to prevent neuropathy in all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer chemotherapy-induced neuropathy prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY

Contacts and locations

Locations

Curie Oncology, Mount Elizabeth Novena Specialist Centre
NOT_YET_RECRUITING

Singapore, 329563, Singapore
National University Hospital
RECRUITING

Singapore, 119074, Singapore

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