CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY

This study aims to understand and potentially prevent a common side effect of chemotherapy called peripheral neuropathy, which causes pain, numbness, and tingling. Researchers are enrolling 45 adults with breast cancer who are starting certain chemotherapy drugs. They will track …

This study is testing a new limb cooling system to see if it can prevent nerve damage, a common and painful side effect of chemotherapy. The research involves 80 cancer patients receiving paclitaxel chemotherapy. Participants will wear special cooling wraps on their arms and legs…

This study is testing a new gel applied to the skin to reduce pain caused by nerve damage from chemotherapy. Sixteen adults with stable, moderate nerve pain will try both the active gel and a placebo gel in different periods to see which works better. The gel is designed to calm …

This study is testing whether a skin patch containing capsaicin (the compound that makes chili peppers hot) works as well as or better than the standard oral medication duloxetine for reducing painful nerve damage caused by chemotherapy. The trial will involve about 274 adults wh…

This study is testing a new way to manage painful nerve damage caused by chemotherapy. About 422 adults with this condition will track their symptoms daily for 12 weeks. Half will get usual care, while the other half will get a prompt phone call from a nurse who can prescribe spe…

This study is testing whether acupuncture can help reduce nerve pain, tingling, and numbness caused by chemotherapy in people with gynecological cancers. It will enroll 75 patients who have finished their chemo. Participants will be randomly assigned to receive real acupuncture, …

This study is testing whether a 10-day treatment with a device called Scrambler Therapy can reduce pain, numbness, and tingling caused by chemotherapy. About 90 adults with these lasting nerve symptoms will be randomly assigned to receive either the real therapy or a sham (preten…

This study aims to see if adding ozone therapy improves the quality of life for adults with severe, treatment-resistant chronic pain and related symptoms. Researchers will observe about 105 patients who are already being treated with ozone at a specialized pain clinic. They will …

This study is testing if wearing a medical compression stocking on one foot during cancer treatment can prevent nerve damage, a common and painful side effect. The trial involves 58 patients with advanced cancers who are receiving a specific type of targeted drug therapy. Researc…

This small study at MD Anderson Cancer Center is testing whether a device that gently stimulates nerves can help reduce pain caused by chemotherapy. It will involve 10 adults who have finished chemo within the last year but still have significant leg pain. The main goal is to see…

This study is testing whether a phone app can teach family caregivers safe massage techniques to help cancer survivors manage long-term nerve pain and numbness caused by chemotherapy. The goal is to see if this at-home care can reduce symptoms for patients and make caregivers fee…

This study is testing whether two cannabis-based treatments (CBD alone or a THC:CBD mix) can reduce chronic nerve pain, tingling, and numbness caused by chemotherapy. It will involve 120 breast and colon cancer survivors who have finished treatment but still suffer from these sid…

This study is testing if a virtual diet coaching program can help reduce nerve pain and numbness caused by chemotherapy. Researchers want to see if a diet low in sugar and high in fiber and healthy fats is practical and acceptable for cancer survivors. The main goal is to check i…

This study is testing if adding ozone therapy to standard care can reduce pain and improve quality of life for cancer patients suffering from nerve damage caused by chemotherapy. It will involve 42 adults who have had persistent, moderate-to-severe nerve pain for at least three m…

This small pilot study is testing whether a new, non-drug approach can help manage nerve pain and numbness caused by chemotherapy. Researchers want to see if it's practical for breast cancer survivors to follow 16 video-guided sessions where they imagine receiving acupuncture. Th…

This study is observing whether a spinal cord stimulation device can help reduce pain and improve quality of life for people suffering from long-term nerve damage caused by chemotherapy. It will follow 20 adults who have already had a successful trial with the device and have not…

This study is testing if using cold wraps with compression on the hands and feet during chemotherapy is as good as cold wraps alone at reducing nerve pain, a common side effect. It involves 190 women with gynecologic cancers like ovarian or cervical cancer who are receiving a spe…

This study is testing whether combining a brain-training therapy called neurofeedback with a medication (duloxetine) works better than either treatment alone for relieving nerve pain caused by chemotherapy. About 380 cancer survivors with this type of pain will be assigned to rec…

This study is testing if wearing special cooling and pressure sleeves on the arms and legs during chemotherapy can help reduce nerve damage. Nerve damage is a common side effect of certain chemo drugs, causing numbness, tingling, and pain. About 50 adults with breast or gynecolog…

This study aims to find a way to predict which breast cancer patients are at high risk for developing severe nerve damage (neuropathy) from paclitaxel chemotherapy. Researchers will test if a specific protein in the blood, measured after the first treatment cycle, can identify pa…