Can a device zap chemo nerve pain? new trial aims to find out

NCT ID NCT07219472

Recruiting now Symptom relief Sponsor: Case Comprehensive Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 06, 2026 · Updated 3 times

Summary

This study tests whether scrambler therapy, a device that sends electrical signals to the skin, can reduce pain, numbness, and tingling from chemotherapy-induced peripheral neuropathy. About 90 adults with persistent nerve pain will receive either real or sham treatment for 10 sessions. Researchers will track changes in pain and quality of life over a year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Scrambler Therapy device
What this could lead to: If it works, this could offer a non-drug option to reduce pain and improve daily life for people with chemotherapy-induced nerve damage.
What could go wrong: This is a small, early-stage study with only 90 people. The sham control means some may not get real treatment, and results may not apply to everyone with nerve pain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chemotherapy-induced neuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY CIPN - CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY

Contacts and locations

Locations

Case Comprehensive Cancer Center, Cleveland Clinic Foundation Taussig Cancer Institute
RECRUITING

Cleveland, Ohio, 44195, United States

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