Socks against side effects: simple stockings may shield nerves during chemo

NCT ID NCT07164950

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether wearing a compression stocking on one foot during antibody-drug conjugate (ADC) infusions can prevent peripheral neuropathy (nerve damage causing numbness or pain). Fifty-eight advanced cancer patients will wear a stocking on their left foot only, while the right foot serves as a comparison. Researchers will track nerve symptoms and quality of life over 24 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

medical-grade compression stocking (20-30 mmHg)

What this could lead to

If it works, this could offer a simple, non-drug way to prevent nerve damage from certain cancer treatments, improving quality of life.

What could go wrong

This is a small, early-phase trial (58 people) with a self-controlled design, so results may not apply broadly. The benefit may be modest or not statistically significant.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neoplasm transitional cell carcinoma urothelial carcinoma chemotherapy-induced neuropathy prevention target peripheral neuropathy prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fudan University Shanghai Cancer Center

    RECRUITING

    Shanghai, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••