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Blood marker may predict chemo nerve damage risk

NCT ID NCT06430814

Recruiting now Knowledge-focused Sponsor: University of Southern Denmark Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study is looking for a way to predict which breast cancer patients will develop nerve damage (peripheral neuropathy) from the chemotherapy drug paclitaxel. Researchers will measure a protein called NFL in the blood after the first round of chemo to see if high levels can identify patients who may need to stop treatment early. The goal is to find a simple blood test that helps doctors personalize chemotherapy and reduce side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help doctors identify patients at high risk for nerve damage before starting paclitaxel, allowing for personalized treatment plans.
What could go wrong
This is an observational study, not a treatment trial. The biomarker being tested may not reliably predict neuropathy in all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer chemotherapy-induced neuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Odense University Hospital

    RECRUITING

    Odense, 5000, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital of Southern Denmark, Sønderborg

    RECRUITING

    Sønderborg, 6400, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital of Southern Denmark, Vejle

    RECRUITING

    Vejle, 7100, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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