Chill out chemo pain: new device may stop nerve damage

NCT ID NCT07064798

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a device that cools and squeezes the arms and legs during chemotherapy to prevent nerve damage, which can cause numbness, tingling, and pain. Fifty adults with breast or gynecologic cancer receiving taxane chemo will wear the device during infusions. Researchers will check if it reduces nerve symptoms, how long people can tolerate it, and if it's safe.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Paxman Limb Cryocompression System (cooling and compression device)

What this could lead to

If it works, this could give patients a simple, drug-free way to prevent or reduce nerve damage from taxane chemotherapy.

What could go wrong

This is a small, early-stage study with only 50 people, so results may not apply to everyone. The device may be uncomfortable or cause skin issues, and it might not reduce nerve symptoms as hoped.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chemotherapy-induced neuropathy peripheral nervous system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••