Could a simple ear device ease chemo nerve pain?

NCT ID NCT07596030

Recruiting now Symptom relief Sponsor: University of Miami Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether people can use a small, portable device at home to stimulate the vagus nerve through the ear. It aims to see if this approach is practical and acceptable for managing nerve pain caused by chemotherapy. The study includes 36 adults who have had platinum or taxane chemotherapy, with 24 having nerve pain and 12 without. Participants with pain will use the device daily for two weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transcutaneous auricular vagus nerve stimulation (taVNS) device
What this could lead to: If this works, it could point toward a safe, at-home way to manage nerve pain from chemotherapy without drugs.
What could go wrong: This is a very small, early feasibility study with only 36 people. It is designed to see if people can use the device at home, not to prove it works for pain. The results may not apply to everyone.

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Conditions

The condition(s) this trial relates to.

chemotherapy-induced neuropathy peripheral nervous system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY

Contacts and locations

Locations

University of Miami, Plumer Building
RECRUITING

Coral Gables, Florida, 33146, United States

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