Could a chili pepper patch soothe chemo nerve pain?
NCT ID NCT06744816
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study is testing whether a capsaicin patch (made from chili peppers) can relieve nerve pain in the feet and legs caused by chemotherapy. Twenty adults who finished chemo within the past year and have lasting pain will try the patch. Researchers will track side effects and check if walking improves.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- capsaicin patch (Qutenza)
- What this could lead to
- If it works, this could point toward a simple topical treatment for chemotherapy-related nerve pain.
- What could go wrong
- This is a very early pilot study with only 20 people, so results may not apply widely. The capsaicin patch can cause burning or skin irritation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a new drug shield nerves from Chemotherapy's side effects?
- Smartwatch could spot nerve damage before it starts
- Could simple leg exercises restore balance and blood flow after chemotherapy?
- Could a simple vibrating pad ease chemo nerve damage?
- Blood test may predict nerve damage from common chemo drug
- Could light therapy ease Chemo's nerve pain?