Could a lung cancer drug work for rare tumors? new trial aims to find out

NCT ID NCT05770037

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a drug called alectinib, already approved for some lung cancers, in people with rare cancers that have a specific genetic change called ALK. About 30 adults, teens, and children with ALK-positive cancers will receive alectinib to see if it shrinks tumors or stops them from growing. The goal is to find new uses for existing drugs in hard-to-treat cancers.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Addenbrooke's Hospital

    RECRUITING

    Cambridge, CB2 OQQ, United Kingdom

  • Alder Hey Hospital

    RECRUITING

    Liverpool, L14 5AB, United Kingdom

  • Belfast City Hospital

    RECRUITING

    Belfast, BT9 7AB, United Kingdom

  • Birmingham Children's Hospital

    NOT_YET_RECRUITING

    Birmingham, United Kingdom

  • Bristol Haematology and Oncology Centre

    RECRUITING

    Bristol, BS2 8ED, United Kingdom

  • Bristol Royal Hospital for Children

    RECRUITING

    Bristol, BS2 8BJ, United Kingdom

  • Cardiff Children's Hospital

    NOT_YET_RECRUITING

    Cardiff, CF14 4XW, United Kingdom

  • Churchill Hospital

    RECRUITING

    Oxford, OX3 7LE, United Kingdom

  • Clatterbridge Cancer Centre

    RECRUITING

    Metropolitan Borough of Wirral, CH63 4JY, United Kingdom

  • Freeman Hospital

    RECRUITING

    Newcastle, NE7 7DN, United Kingdom

  • Great North Children's Hospital

    RECRUITING

    Newcastle, NE1 4LP, United Kingdom

  • Great Ormond Street Hospital

    RECRUITING

    London, WC1N 3JH, United Kingdom

  • Guy's Hospital

    RECRUITING

    London, SE1 9RT, United Kingdom

  • John Radcliffe Hospital

    RECRUITING

    Oxford, OX3 9DU, United Kingdom

  • Leicester Royal Infirmary

    RECRUITING

    Leicester, LE1 5WW, United Kingdom

  • Royal Hospital for Children Glasgow

    RECRUITING

    Glasgow, G51 4TF, United Kingdom

  • Royal Manchester Children's Hospital

    NOT_YET_RECRUITING

    Manchester, M13 9WL, United Kingdom

  • Sheffield's Children's Hospital

    RECRUITING

    Sheffield, S10 2TH, United Kingdom

  • Southampton General Hospital

    RECRUITING

    Southampton, SO16 6YD, United Kingdom

  • The Beatson Hospital

    RECRUITING

    Glasgow, G12 OYN, United Kingdom

  • The Christie Hospital

    RECRUITING

    Manchester, M20 4BX, United Kingdom

  • The Royal Marsden Hospital

    RECRUITING

    Sutton, SM2 5PT, United Kingdom

  • University College London Hospital

    RECRUITING

    London, NW1 2BU, United Kingdom

  • University Hospital Birmingham

    RECRUITING

    Birmingham, B15 2TT, United Kingdom

  • Velindre Cancer Centre

    RECRUITING

    Cardiff, CF14 2TL, United Kingdom

  • Western General Hospital

    RECRUITING

    Edinburgh, EH4 2XU, United Kingdom

  • Weston Park Hospital

    RECRUITING

    Sheffield, S10 2SJ, United Kingdom

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Other studies related to the condition(s) this trial covers.