Could a lung cancer drug work for other rare tumors? new trial aims to find out.

NCT ID NCT06988475

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests capmatinib, a drug already approved for certain lung cancers, in adults with rare cancers that have specific MET gene changes. About 30 participants will receive the drug to see if it can shrink tumors or stop them from growing for at least 24 weeks. The goal is to find new uses for existing targeted therapies in hard-to-treat cancers.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Addenbrooke's Hospital

    NOT_YET_RECRUITING

    Cambridge, CB2 OQQ, United Kingdom

  • Belfast City Hospital

    RECRUITING

    Belfast, BT9 7AB, United Kingdom

  • Bristol Haematology and Oncology Centre

    RECRUITING

    Bristol, BS2 8ED, United Kingdom

  • Churchill Hospital

    RECRUITING

    Oxford, OX3 7LE, United Kingdom

  • Clatterbridge Cancer Centre

    RECRUITING

    Metropolitan Borough of Wirral, CH63 4JY, United Kingdom

  • Freeman Hospital

    RECRUITING

    Newcastle, NE7 7DN, United Kingdom

  • Guy's Hospital

    RECRUITING

    London, SE1 9RT, United Kingdom

  • Leicester Royal Infirmary

    RECRUITING

    Leicester, LE1 5WW, United Kingdom

  • Royal Marsden Hospital

    RECRUITING

    Sutton, SM2 5PT, United Kingdom

  • Southampton General Hospital

    RECRUITING

    Southampton, SO16 6YD, United Kingdom

  • The Beatson Hospital

    RECRUITING

    Glasgow, G12 OYN, United Kingdom

  • The Christie Hospital

    RECRUITING

    Manchester, M20 4BX, United Kingdom

  • University College London Hospital

    RECRUITING

    London, NW1 2BU, United Kingdom

  • University Hospital Birmingham

    RECRUITING

    Birmingham, B15 2TT, United Kingdom

  • Velindre Cancer Centre

    RECRUITING

    Cardiff, CF14 2TL, United Kingdom

  • Western General Hospital

    RECRUITING

    Edinburgh, EH4 2XU, United Kingdom

  • Western Park Hospital

    RECRUITING

    Sheffield, S10 2SJ, United Kingdom

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