MALIGNANCY

This trial is testing if a drug called capmatinib, already used for some lung cancers, can help adults with rare or uncommon cancers that have specific changes in a gene called MET. The goal is to see if the drug shrinks tumors or provides long-term benefit for these hard-to-trea…

This study compares two different materials used to rebuild the chest wall after surgery to remove tumors. It will follow 50 patients in Pakistan to see if using twisted steel wires works as well as or better than traditional bone cement. Researchers will look at pain levels, bre…

This trial is testing if an existing immunotherapy drug called atezolizumab can help control rare cancers or common cancers with rare genetic features. It will involve about 30 adults and children whose cancers have specific genetic markers. The goal is to see if this approved dr…

This trial is testing if a drug called entrectinib, already approved for some lung cancers, can help control other rare cancers that share the same genetic change (called ROS1-positive). It aims to enroll about 30 adults and children with these rare cancers to see if the drug shr…

This study is testing new radioactive tracer chemicals for PET/CT scans to see if they can better detect and monitor cancers of the digestive system, including stomach, colon, liver, and pancreatic cancer. About 400 adults with confirmed or suspected digestive cancer will receive…

This study is creating a national collection of blood and tissue samples from cancer patients who experience serious side effects from immunotherapy drugs. Researchers will collect samples and review medical records to build a resource for future studies. The goal is to help scie…

This study is testing different outreach methods to see which ones work best to increase enrollment of African American patients in early-phase cancer treatment trials. It will enroll both patients and their doctors to receive different recruitment approaches or no special outrea…