MALIGNANCY

This study looks at a rare, often fatal disease called KSHV-associated multicentric Castleman's disease (MCD), caused by a virus. Researchers want to understand how the disease works and test several experimental treatments, including high-dose zidovudine, valganciclovir, bortezo…

This study looks at whether support from community health workers can help African American patients with advanced cancer feel better and have a higher quality of life. About 160 patients will either get standard care or standard care plus extra help from a community health worke…

This study collects medical information and biological samples from 32 cancer patients starting or restarting immunotherapy. The goal is to better understand why some patients develop immune-related side effects and how to manage them. Researchers hope this knowledge will improve…

This study was designed to track how the immune system recovers after CAR-T cell therapy and whether a pneumonia vaccine (PCV-21) given six months later can work. It planned to enroll 50 adults with blood cancers or solid tumors. However, the study was withdrawn before any partic…

This study compares different outreach strategies to see which works best for enrolling African American patients into early-phase cancer treatment trials. About 134 patients and their doctors will take part, with some receiving special outreach and others standard care. The goal…

This study was designed to test a new imaging agent called 68Ga-FAPI-46 in people with solid tumors. The goal was to see if a PET/CT scan using this agent could predict how well a patient's tumor would respond to antibody-based therapy. The study was withdrawn before enrolling an…