MALIGNANCY

This study tests capmatinib, a drug already approved for certain lung cancers, in adults with other rare cancers that have specific MET gene changes. About 30 participants will receive the drug to see if their tumors shrink or stop growing for at least 24 weeks. The goal is to fi…

This study compares two ways to rebuild the chest wall after removing a tumor: using twisted steel wires or bone cement. The goal is to see which method causes less pain, fewer complications, and is more cost-effective. About 50 adults needing this surgery will take part, and res…

This study tests a drug called entrectinib, already approved for certain lung and solid tumors, in people with rare cancers that have a specific genetic change called ROS1 fusion. About 30 adults, teens, and children with these rare cancers will receive the drug. Researchers will…

This trial tests a drug called atezolizumab, already approved for some cancers, in people with rare cancers that have high numbers of genetic mutations or specific DNA repair problems. About 30 adults and children with these rare tumor types will receive the drug. The main goal i…

This study is testing a new type of PET/CT imaging that uses special probes to target and highlight digestive system cancers, including cancers of the liver, stomach, colon, pancreas, and more. Researchers want to see how these probes spread in the body and how well they can find…

This study is creating a national collection of blood, tissue, and medical information from 240 cancer patients who have experienced serious side effects from immunotherapy. The goal is to store these samples for future research, so scientists can better understand why these side…

This study looks at whether repeated sessions of hyperbaric oxygen therapy (HBOT) can damage DNA in people who have had radiation for cancer. HBOT is used to help heal tissue damage from radiation, but it also creates reactive oxygen molecules that might harm cells. Researchers w…