One-Shot radiation hope for bulky tumors

NCT ID NCT02333110

Recruiting now Symptom relief Sponsor: Sir Mortimer B. Davis - Jewish General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a single, high-dose radiation treatment called spatially fractionated radiation (SFR) for people with large tumors (over 8 cm) or tumors that resist standard radiation. The goal is to see if one session can relieve symptoms as well as multiple sessions, with fewer side effects and less time at the hospital. Fifty participants will receive the treatment and be monitored for pain relief and side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: spatially fractionated radiation therapy (GRID radiation)
What this could lead to: If it works, this could offer a quicker, single-session radiation option to relieve symptoms from large or stubborn tumors, reducing hospital visits.
What could go wrong: This is a small, early-phase study (50 people) testing a new technique. It may not work for all tumor types, and there are risks of side effects like pain or tissue damage.

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Conditions

The condition(s) this trial relates to.

cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PATIENTS WITH SYMPTOMATIC OR BULKY TUMORS (MORE THAN 8 CM) OR WITH TUMORS RESISTANT TO RADIATION

Contacts and locations

Locations

Sir Mortimer Jewish General Hospital
RECRUITING

Montreal, Quebec, H3T 1E2, Canada

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