New radiation method aims to shrink large tumors

NCT ID NCT07647679

Not yet recruiting Symptom relief Sponsor: Duke University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This pilot study tests whether adding a specialized radiation technique called Lattice Radiation Therapy (LRT) to standard palliative radiation can safely shrink large tumors (at least 4.5 cm) in adults. The study will enroll 25 people with various cancers who are already scheduled for palliative radiation. Participants receive one extra LRT treatment before starting standard radiation, and researchers will monitor side effects and tumor shrinkage for one year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Lattice Radiation Therapy (LRT)
What this could lead to: If it works, this could offer a new way to shrink large tumors that are hard to treat with standard radiation alone.
What could go wrong: This is a very small pilot study (25 people) with no control group, so results may not apply broadly. It only tests safety and early effectiveness, not a proven treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LARGE TUMOR PALLIATIVE RADIOTHERAPY

Contacts and locations

Locations

Duke Cancer Center

Durham, North Carolina, 27710, United States

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