Could a zap to the brain's master gland ease cancer pain?

NCT ID NCT06287515

First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 2 times

Summary

This early-stage study tests whether a precise radiation dose to the pituitary gland (hypophysectomy) can safely reduce severe cancer pain that hasn't responded to standard treatments like opioids. About 40 adults with advanced cancer and hard-to-control pain will receive this one-time, non-invasive procedure. The main goal is to check for side effects and see if pain improves.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

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Other studies related to the condition(s) this trial covers.