Which cancer care model boosts quality of life? large trial seeks answers

NCT ID NCT05297734

Recruiting now Symptom relief Sponsor: Stanford University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two approaches to supportive cancer care for nearly 3,000 adults with cancer. One group gets information through email or their health record, while the other works one-on-one with a lay health worker over 12 months. The goal is to see which model better improves quality of life and helps with advance care planning.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Supportive cancer care models (technology-based vs. team-based with lay health workers)
What this could lead to: If successful, this could show which care model better helps cancer patients manage symptoms and plan future care, improving their quality of life.
What could go wrong: This is a comparative effectiveness trial, not testing a new drug or cure. The results may show only small differences between the two approaches, and benefits may vary by patient.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast neoplasm bronchogenic carcinoma cancer carcinoma Carcinoma, Ovarian Epithelial colonic neoplasm Death Disease Progression epithelial neoplasm Esophageal Neoplasms gastric neoplasm glioblastoma lung disorder lung neoplasm melanoma Myelodysplastic Syndromes neoplasm Neoplasms by Histologic Type Neoplasms by Site non-small cell lung carcinoma osteosarcoma ovarian cancer pancreatic neoplasm rectal neoplasm renal cell carcinoma respiratory system disorder respiratory tract neoplasm sarcoma skin neoplasm small cell lung carcinoma Thoracic Neoplasms Urogenital Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANCER END OF LIFE

Contacts and locations

Locations

Beckman Research Institute of City of Hope
RECRUITING

Duarte, California, 91010, United States
George E. Wahlen Department of Veterans Affairs Medical Center
RECRUITING

Salt Lake City, Utah, 84148, United States
Kaiser Foundation Research Institute
RECRUITING

San Francisco, California, 94115, United States
North Las Vegas VA Medical Center
ACTIVE_NOT_RECRUITING

Las Vegas, Nevada, 89086, United States
Oncology Institute for Hope and Innovation
RECRUITING

Los Angeles, California, 90017, United States
Pacific Cancer Care
ACTIVE_NOT_RECRUITING

Monterey, California, 93940, United States
Sacramento VA Medical Center - VA Northern California Health Care System
ACTIVE_NOT_RECRUITING

Mather, California, 95655, United States
San Francisco VA Medical Center
ACTIVE_NOT_RECRUITING

San Francisco, California, 94121, United States
Santa Clara Valley Medical Center
RECRUITING

Fruitdale, California, 95128, United States
Spark M. Matsunaga VA Medical Center
RECRUITING

Honolulu, Hawaii, 96819, United States
St Jude Heritage Medical Group
RECRUITING

Fullerton, California, 92835, United States
University of Alabama at Birmingham
RECRUITING

Birmingham, Alabama, 35294, United States
University of San Francisco
RECRUITING

San Francisco, California, 94117, United States
University of South Alabama
RECRUITING

Mobile, Alabama, 36688, United States
VA Medical Center, Fresno
RECRUITING

Fresno, California, 93703, United States
VA Palo Alto
ACTIVE_NOT_RECRUITING

Palo Alto, California, 94305, United States
Zuckerberg San Francisco General
RECRUITING

San Francisco, California, 94110, United States

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