Can a smartphone app lift depression in incurable cancer patients?

NCT ID NCT06582784

Recruiting now Symptom relief Sponsor: Medical University of South Carolina Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a mobile app called Moodivate that helps people with incurable cancer track their daily activities and mood, and suggests new activities to improve their mood. About 279 participants will be randomly assigned to use the app or receive usual care for 8 weeks, with follow-up at 12 weeks. The goal is to see if the app can reduce depression symptoms and improve quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Moodivate mobile app (behavioral activation therapy)
What this could lead to: If it works, this could provide a convenient, low-cost way to ease depression in people with incurable cancer.
What could go wrong: This is a small, early-stage trial with no placebo control. The app may not improve mood more than usual care, and some people may find it frustrating or emotionally distressing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer Depression depressive disorder neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANCER DEPRESSION DEPRESSIVE SYMPTOMS

Contacts and locations

Locations

Medical University of South Carolina
RECRUITING

Charleston, South Carolina, 29425, United States

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