DEPRESSIVE SYMPTOMS
Clinical trials for DEPRESSIVE SYMPTOMS explained in plain language.
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Can moving your body and mind together tame diabetes?
Disease control Recruiting nowThis study is testing if adding guided exercise to a standard talk therapy program helps Black men with type 2 diabetes better control their blood sugar and feel better mentally. It will involve 80 men over 7 months, with sessions held online. The goal is to see if this combined …
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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New online program shields teens from anxiety and depression
Prevention Recruiting nowThis study tested an 8-session online group program designed to prevent anxiety and depression in teenagers identified as being at high risk. The program, called PROCARE-I+, teaches skills for managing emotions and improving well-being. Researchers measured whether the program im…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: University of Jaén • Aim: Prevention
Last updated Apr 01, 2026 14:40 UTC
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Brain-Saving plan for depressed adults: exercise, diet & training tested
Prevention Recruiting nowThis study is testing whether lifestyle changes can help prevent memory and thinking problems in adults aged 50-80 who have depression or depressive symptoms. Participants will try different 12-week programs involving supervised exercise, brain training games, or Mediterranean di…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: IRCCS Centro San Giovanni di Dio Fatebenefratelli • Aim: Prevention
Last updated Mar 30, 2026 14:30 UTC
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Can fighting racism fight depression? new study tests activism as health intervention
Prevention Recruiting nowThis study is testing whether a program that teaches racial justice activism can prevent depression and improve physical health in Black and Latinx teenagers and young adults. Researchers will enroll 300 participants aged 15-20 in Chicago. Half will receive activism training, whi…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago • Aim: Prevention
Last updated Mar 27, 2026 12:40 UTC
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Brain scans reveal if music therapy eases student stress
Symptom relief Recruiting nowThis study is testing whether a specific type of music therapy, where students write songs, can help reduce feelings of depression, anxiety, and stress while improving social connections. Researchers will compare songwriting sessions to simple music listening and discussion in 20…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: The University of Hong Kong • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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Can writing heal wounds? VA tests new therapy for LGBTQ+ Veterans' mental health
Symptom relief Recruiting nowThis study is testing if a brief writing exercise can help reduce symptoms of depression and anxiety in LGBTQ+ veterans. The therapy involves three sessions where participants write about stressful experiences related to their sexual identity. Researchers want to see if this simp…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Apr 01, 2026 14:40 UTC
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New hope for moms: device combo targets Post-Birth depression and incontinence
Symptom relief Recruiting nowThis study is testing whether a combination of two non-invasive medical devices can help improve symptoms of depression and urinary incontinence in women who have given birth within the last five years. Participants will receive either the real treatment or a very low-level 'sham…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: BTL Industries Ltd. • Aim: Symptom relief
Last updated Mar 31, 2026 12:11 UTC
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Meditation program aims to ease student stress and anxiety
Symptom relief Recruiting nowThis study is testing an 8-week group program that teaches meditation, mindfulness, and relaxation techniques to help medical and graduate students manage their mood. The program aims to reduce symptoms of anxiety and depression through mind-body skills. Researchers will compare …
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: Weill Medical College of Cornell University • Aim: Symptom relief
Last updated Mar 31, 2026 12:11 UTC
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New device combo aims to lift menopause fog and revive intimacy
Symptom relief Recruiting nowThis study is testing whether a combination of two non-invasive medical devices can help improve common challenges faced by women during and after menopause. It aims to see if the treatment can reduce depressive symptoms, improve sexual function, and lessen urinary incontinence. …
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: BTL Industries Ltd. • Aim: Symptom relief
Last updated Mar 31, 2026 12:11 UTC
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Brain scans probe CBD's power against pain and depression
Symptom relief Recruiting nowThis study is testing whether cannabidiol (CBD) can reduce inflammation in the brains of people with chronic low back pain, some of whom also have mild to moderate depression. Researchers will use special brain scans to measure inflammation before and after participants take eith…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Mar 30, 2026 14:34 UTC
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New online program aims to ease menopause sleep woes
Symptom relief Recruiting nowThis study is testing whether an online education program about healthy sleep habits can help women going through menopause sleep better and feel less depressed. 500 women with poor sleep will be randomly assigned to either receive the sleep education or be in a control group. Re…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: Ankara Yildirim Beyazıt University • Aim: Symptom relief
Last updated Mar 30, 2026 14:30 UTC
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VR headsets aim to soothe burn Survivors' lingering pain and distress
Symptom relief Recruiting nowThis study is testing whether a common relaxation technique is more helpful for burn survivors when it's delivered through virtual reality (VR). Adult burn survivors with ongoing symptoms like pain, itch, or anxiety will try both a standard relaxation program and a VR-enhanced ve…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Mar 30, 2026 14:30 UTC
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New app aims to ease the 'Silent Suffering' of breast cancer survivors
Symptom relief Recruiting nowThis study is testing a culturally tailored web and mobile app designed to help Asian American women who have survived breast cancer. The app provides personalized information and coaching to help them manage chronic pain and feelings of depression that often linger after treatme…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: University of Texas at Austin • Aim: Symptom relief
Last updated Mar 30, 2026 14:29 UTC
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Digital bridge to healing: online therapy tailored for refugee youth
Symptom relief Recruiting nowThis study is testing a 10-week online therapy program designed specifically for Farsi/Dari-speaking young migrants and refugees. It aims to help reduce symptoms of anxiety, depression, grief, and stress. Participants will be randomly assigned to either receive the therapy immedi…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: Karolinska Institutet • Aim: Symptom relief
Last updated Mar 30, 2026 14:29 UTC
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Can ancient moves ease modern depression? online tai chi tested for HIV patients
Symptom relief Recruiting nowThis study is testing if taking Tai Chi classes online can help reduce feelings of depression in older adults living with HIV. Researchers will compare a 12-week online Tai Chi program to online health education classes to see which is better at improving mood. They are recruitin…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: Florida International University • Aim: Symptom relief
Last updated Mar 30, 2026 14:28 UTC
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Shining a light on depression: simple therapy tested for vulnerable group
Symptom relief Recruiting nowThis study is testing whether a simple, non-drug treatment called bright light therapy can help reduce feelings of depression in adults with intellectual disabilities. The researchers are working with care organizations to see how practical and acceptable this therapy is for both…
Matched conditions: DEPRESSIVE SYMPTOMS
Sponsor: Erasmus Medical Center • Aim: Symptom relief
Last updated Mar 27, 2026 12:40 UTC
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Magic mushroom drug tested to lift depression in Alzheimer's patients
Symptom relief Recruiting nowThis small, early-stage study from Johns Hopkins University is testing whether the psychedelic compound psilocybin, given in a controlled setting with support, can safely reduce depression in people with mild cognitive impairment or early Alzheimer's disease. Up to 20 participant…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: EARLY_PHASE1 • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Mar 24, 2026 12:02 UTC
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Phone app aims to lift spirits for those battling advanced cancer
Symptom relief Recruiting nowThis study is testing if a smartphone app called 'Moodivate' can help reduce depression in people living with incurable cancer. About 279 participants will be randomly chosen to either use the app or not for 12 weeks. The goal is to see if this easy-to-access digital tool can imp…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated Mar 24, 2026 12:02 UTC
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Phone app aims to cut opioid use after joint surgery
Symptom relief Recruiting nowThis study is testing a smartphone app designed to help people recover from knee or hip replacement surgery. The app uses digital therapy techniques and coach support to help patients manage anxiety, depression, and pain. Researchers want to see if using the app can help patients…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Mar 16, 2026 15:26 UTC
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Scientists track 500 patients to unlock secrets of mood disorder recovery
Knowledge-focused Recruiting nowThis study aims to understand how people with depression or bipolar disorder respond to their regular treatments. Researchers will observe 500 adults already receiving care, tracking their symptoms weekly for about 12 weeks. The goal is to find patterns that might help predict wh…
Matched conditions: DEPRESSIVE SYMPTOMS
Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:09 UTC
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Scientists probe the Brain's role in beating the blues
Knowledge-focused Recruiting nowThis study aims to understand how two different programs—Mindfulness-Based Cognitive Therapy and a general Wellness class—affect specific thinking skills related to emotions in people with mild to moderate depression symptoms. Researchers will measure how well participants can ma…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: Butler Hospital • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:03 UTC
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Researchers probe hidden mental toll of diabetes
Knowledge-focused Recruiting nowThis study aims to understand how mental health, depression, and quality of life are connected in adults living with type 2 diabetes. Researchers will survey 500 patients at a Taiwan hospital clinic using standard questionnaires. The goal is to identify factors that affect well-b…
Matched conditions: DEPRESSIVE SYMPTOMS
Sponsor: National Taiwan University Hospital • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:17 UTC
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Scientists ask kids: what stresses you out?
Knowledge-focused Recruiting nowThis study aims to understand the daily challenges and stressors faced by children aged 8-12 who have depressive symptoms. Researchers will interview the children and hold focus groups with their parents to learn what situations cause emotional difficulty and how they cope. The i…
Matched conditions: DEPRESSIVE SYMPTOMS
Sponsor: Ludwig-Maximilians - University of Munich • Aim: Knowledge-focused
Last updated Mar 13, 2026 15:05 UTC