DEPRESSIVE SYMPTOMS
Clinical trials for DEPRESSIVE SYMPTOMS explained in plain language.
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New program helps older adults fight loneliness and pain without pills
Symptom relief OngoingThis study tests a program called RESET, led by community health workers, to help older adults in Detroit improve their physical and mental well-being. About 456 African American adults aged 50 and older with symptoms like depression, anxiety, chronic pain, or loneliness will tak…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated May 17, 2026 06:21 UTC
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Can mindfulness ease migraines and low mood?
Symptom relief OngoingThis study tests whether mindfulness-based cognitive therapy delivered by phone or video can help people with both migraine and depressive symptoms. 145 adults with 4-20 headache days per month and mild to moderate depression are taking part. The goal is to see if the program is …
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: Amanda Shallcross • Aim: Symptom relief
Last updated May 14, 2026 12:03 UTC
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Virtual reality could lift spirits of kidney patients on dialysis
Symptom relief OngoingThis study tests whether a virtual reality (VR) program can help ease depression and improve quality of life for people on hemodialysis. About 61 adults with kidney failure and depressive symptoms will use a VR headset to practice positive thinking skills over 5 weeks. The goal i…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: University of Illinois at Urbana-Champaign • Aim: Symptom relief
Last updated May 13, 2026 16:04 UTC
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Phone therapy boosts antidepressants in new study
Symptom relief OngoingThis study tests whether a smartphone app with cognitive behavioral therapy (CBT) can further reduce depressive symptoms in adults already taking antidepressants. About 150 people in Sweden will use the app for 9 weeks, with extra online materials and therapist support available.…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: Linkoeping University • Aim: Symptom relief
Last updated May 05, 2026 11:54 UTC
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New program aims to boost mental health care for brain injury survivors
Knowledge-focused ENROLLING_BY_INVITATIONThis study tests a training program for occupational therapists who work with people who have had a brain injury. The goal is to help therapists better screen for and treat anxiety and depression in their patients. Twenty therapists will participate, and researchers will see if t…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: Colorado State University • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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Texas launches massive youth depression & suicide research network
Knowledge-focused ENROLLING_BY_INVITATIONThis study is creating a large registry of 5,000 young people (ages 8-20) in Texas who have depression or thoughts of suicide. Researchers will collect health information over time to better understand these conditions and develop tools to predict outcomes. The goal is to improve…
Matched conditions: DEPRESSIVE SYMPTOMS
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated May 14, 2026 12:02 UTC
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Brain scans reveal how cannabis may help veterans with PTSD and suicidal thoughts
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at how different types of cannabis affect the brains of U.S. military veterans with PTSD. Up to 100 veterans will get brain scans before and after 12 weeks of using cannabis. The goal is to see changes in brain inflammation, communication, and activity linked to …
Matched conditions: DEPRESSIVE SYMPTOMS
Sponsor: Wayne State University • Aim: Knowledge-focused
Last updated May 04, 2026 16:31 UTC