DEPRESSIVE SYMPTOMS
Clinical trials for DEPRESSIVE SYMPTOMS explained in plain language.
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Mindfulness by phone or video may ease migraines and low mood
Symptom relief OngoingThis study tests whether a mindfulness-based program (MBCT) delivered by phone or video can help people with migraines and depressive symptoms. About 145 adults with 4-20 headache days per month and mild to moderate depression will be randomly assigned to phone, video, or usual c…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: Amanda Shallcross • Aim: Symptom relief
Last updated Jul 22, 2026 00:00 UTC
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Can a smartphone app lift depression? new study puts syrenity to the test
Symptom relief TerminatedThis study investigates whether the Syrenity mental health app can reduce depressive symptoms in adults with moderate to severe depression. Participants use the app, which includes exposure-based and behavioral activation exercises, and their progress is tracked with weekly quest…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: Indiana University • Aim: Symptom relief
Last updated Jul 04, 2026 00:00 UTC
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Can a VR vacation lift depression in dialysis patients?
Symptom relief OngoingThis study tests whether a 5-week virtual reality program that teaches positive thinking skills can help reduce depression and improve quality of life in people on hemodialysis. Sixty-one adults with end-stage kidney disease and mild-to-moderate depressive symptoms will either re…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: University of Illinois at Urbana-Champaign • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Can a phone app boost depression treatment?
Symptom relief OngoingThis study tests whether a smartphone app based on cognitive behavioral therapy (CBT) can help adults who are already taking antidepressants feel better. 150 participants in Sweden will use the app for 9 weeks, with extra online materials and therapist support available. The goal…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: Linkoeping University • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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Can cannabis calm the brain? new study scans Veterans' brains for clues
Knowledge-focused ENROLLING_BY_INVITATIONThis study will use brain scans to see how cannabis affects inflammation and brain activity in up to 100 U.S. military veterans with PTSD and suicidal thoughts. Participants will take cannabis for 12 weeks and have PET and MRI scans before and after. The goal is to link brain cha…
Matched conditions: DEPRESSIVE SYMPTOMS
Sponsor: Wayne State University • Aim: Knowledge-focused
Last updated Aug 08, 2026 00:03 UTC
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Mindfulness may rewire depressed brains, small study hints
Knowledge-focused OngoingThis study looks at whether mindfulness-based cognitive therapy (MBCT) can improve how the brain controls emotions in people with mild depression symptoms. 76 adults with depression in remission will be randomly assigned to either MBCT or a wellness program. Researchers will use …
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: Butler Hospital • Aim: Knowledge-focused
Last updated Jul 08, 2026 00:00 UTC
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Massive texas study aims to predict and prevent teen suicide
Knowledge-focused ENROLLING_BY_INVITATIONThis study is creating a large registry of 5,000 young people aged 8 to 20 who have depression or suicidal thoughts. Researchers will collect data from clinics across Texas to better understand these conditions and develop models to predict outcomes. The goal is to improve popula…
Matched conditions: DEPRESSIVE SYMPTOMS
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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New program aims to help therapists tackle depression after brain injury
Knowledge-focused ENROLLING_BY_INVITATIONThis study tests a training program for occupational therapists who work with adults who have had a brain injury. The goal is to help therapists better spot and treat anxiety and depression in their patients. Twenty therapists will take part, and researchers will see if they star…
Matched conditions: DEPRESSIVE SYMPTOMS
Phase: NA • Sponsor: Colorado State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC